Comorbidity of obsessive-compulsive disorder and symptoms with nicotine dependence: Observational epidemiologic evidence from US-representative and psychiatric outpatient population-based samples.
Comorbidity of obsessive-compulsive disorder and symptoms with nicotine dependence: Observational epidemiologic evidence from US-representative and psychiatric outpatient population-based samples.
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DOI：
10.1016/j.jpsychires.2021.12.020
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发表时间：
2022-03
影响因子：
4.8
通讯作者：
Leventhal AM
中科院分区：
文献类型：
--
作者：
Chasson GS;Cho J;Zimmerman M;Leventhal AM
尽管有新的证据表明强迫症和症状（OCS）与尼古丁依赖（ND）有关，但这种共病几乎没有得到研究。为了解决这一问题，目前的调查强调了两个流行病学数据集中这种合并症的证据：（1）美国全国代表性调查（即，国家科摩罗研究-复制; NCS-R），和（2）精神病临床流行病学数据集（即，改善诊断评估和服务的方法（MIDAS）。对于NCS-R（n=2088），进行访谈作为广泛数据收集的一部分，包括OCS症状计数和ND诊断。对于MIDAS（n=1257），作为在美国医院门诊治疗计划中接受心理健康服务的一部分，参与者接受了诊断访谈，包括ND和强迫症（OCD）的评估，OCS的特征是自我报告的症状计数。NCS-R的结果表明，随着OCS症状计数的增加，当前ND的发生率从3.1%增加到10.8%。MIDAS临床样本的结果显示出类似的趋势，但与美国代表性NCS-R样本相比，总体数字更高，随着OCS计数的增加，当前ND的比率从18.3%增加到41.4%。在这两个数据集中，在调整精神病学和社会人口统计学协变量后，OCS与当前（而非既往）ND呈正相关。对于MIDAS，在调整协变量后，强迫症诊断状态与ND无关。本研究的结果支持临床和非临床人群中的OCS-ND共病，并表明当强迫症现象被建模为二分诊断变量与维度结构时，OCS-ND联系可能会被掩盖。
Despite emerging evidence linking obsessive-compulsive disorder and symptoms (OCS) and nicotine dependence (ND), this comorbidity has received little research. To address this, the current investigation highlights evidence of this comorbidity in two epidemiologic datasets: (1) US nationally-representative survey (i.e., National Comorbidity Study-Replication; NCS-R), and (2) a psychiatric clinical epidemiology dataset (i.e., the Methods to Improve Diagnostic Assessment and Services; MIDAS). For NCS-R (n=2088), interviews were carried as part of extensive data collection, including OCS symptom count and ND diagnosis. For MIDAS (n=1257), as part of receiving mental health services at a US hospital outpatient treatment program, participants received diagnostic interviews, including evaluation of ND and obsessive-compulsive disorder (OCD), with OCS being characterized by self-reported symptom count. Results from NCS-R indicate that rates of current ND increased from 3.1% to 10.8% as OCS symptom count increased. Results from the MIDAS clinical sample exhibited a similar trend, but with higher overall figures compared to the US-representative NCS-R sample, with rates of current ND increasing from 18.3% to 41.4% as OCS count increased. In both datasets, OCS was positively associated with current (but not prior) ND after adjusting for psychiatric and sociodemographic covariates. For MIDAS, after adjusting for covariates, OCD diagnostic status was not associated with ND. Findings from this study lend support for the OCS-ND comorbidity in clinical and non-clinical populations and suggests that the OCS-ND link may be obscured when obsessive-compulsive phenomena is modeled as a dichotomous diagnostic variable versus as a dimensional construct.
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影响因子：
4.5
作者：
Lawrence D;Mitrou F;Zubrick SR
通讯作者：
Zubrick SR
影响因子：
120.7
作者：
Lasser, K;Boyd, JW;Bor, DH
通讯作者：
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影响因子：
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作者：
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Lieb, Roselind
DOI：
10.1007/s004060170047
发表时间：
2001-06-01
影响因子：
4.7
作者：
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通讯作者：
John, U
影响因子：
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作者：
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