Analysis of the BOLD Characteristics in Pass-Band bSSFP fMRI.
Analysis of the BOLD Characteristics in Pass-Band bSSFP fMRI.
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DOI：
10.1002/ima.21296
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发表时间：
2012-03-01
影响因子：
3.3
通讯作者：
Pauly, John M.
中科院分区：
文献类型：
--
作者：
Kim, Taek Soo;Lee, Jongho;Lee, Jin Hyung;Glover, Gary H.;Pauly, John M.
平衡稳态自由进动(BSSFP)被认为是获得血氧水平依赖对比度的一种替代方法。特别是，通带bSSFP功能磁共振成像(FMRI)被认为在bSSFP轮廓的相对宽而平的非共振频带中利用了bSSFP的T2敏感性。与传统方法相比，该方法有可能提供更高的信噪比(SNR)效率，同时减少成像伪影。以往的实验结果表明，序列参数对功能对比度的高低及其特征有显著影响。然而，很少有人对这些对比特性进行系统的研究。在这项研究中，通过计算机模拟来研究功能对比度的来源以及扫描参数对功能对比度的影响，以阐明通带bSSFP功能磁共振成像的对比度特性。通过实验对仿真结果进行了验证。
Balanced steady-state free precession (bSSFP) has been proposed as an alternative method to acquire the blood oxygenation level dependent contrast. Particularly, pass-band bSSFP functional magnetic resonance imaging (fMRI) is believed to utilize the T2 sensitivity of bSSFP in a relatively wide and flat off-resonance frequency band of the bSSFP profile. The method has a potential to provide higher signal to noise ratio (SNR) efficiency with reduced imaging artifacts compared to conventional approaches. Previous experimental results suggested that the level of the functional contrast and its characteristics are significantly influenced by the sequence parameters. However, few of these contrast characteristics have been investigated systematically. In this study, a computer simulation was performed to investigate the sources of functional contrast and the influence of scan parameters on the functional contrast to elucidate the contrast characteristics of pass-band bSSFP fMRI. Experiments were performed to validate the simulation results.
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影响因子：
3.3
作者：
Lee, Jongho;Shahram, Morteza;Pauly, John M.
通讯作者：
Pauly, John M.
影响因子：
3.3
作者：
Lee, J;Santos, JM;Pauly, JM
通讯作者：
Pauly, JM
影响因子：
3.3
作者：
Miller, KL;Smith, SM;Pauly, JM
通讯作者：
Pauly, JM
影响因子：
64.8
作者：
通讯作者：
--
影响因子：
3.3
作者：
Lee, Jin Hyung;Dumoulin, Serge O.;Pauly, John M.
通讯作者：
Pauly, John M.