Changes in condom use during the first year of HIV treatment in Uganda and the relationship to depression.

Changes in condom use during the first year of HIV treatment in Uganda and the relationship to depression.
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DOI:
10.1007/s12160-013-9586-3
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发表时间:
2014-10
影响因子:
3.8
通讯作者:
Musisi, Seggane
Musisi, Seggane
中科院分区:
心理学2区
文献类型:
--
作者:
Wagner, Glenn J.;Ghosh-Dastidar, Bonnie;Slaughter, Mary Ellen;Akena, Dickens;Nakasujja, Noeline;Musisi, Seggane

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我们研究了抗逆转录病毒治疗(ART)的效果,以及抑郁症的预测作用,与主要合作伙伴使用避孕套。来自乌干达的三项研究的数据被合并到750名有主要性伴侣的患者样本中,其中502人开始ART,248人进入艾滋病毒护理,并随访12个月。随机效应逻辑回归模型被用来检查抗逆转录病毒疗法的影响,以及基线水平和抑郁症变化对主要伴侣使用避孕套的影响。在第12个月,61%的ART患者和67%的非ART患者始终使用避孕套,而基线时分别为44%和41%。多变量分析显示,ART和非ART患者一致使用避孕套的增加相似,基线时的轻度抑郁和随着时间的推移抑郁的增加预测不一致的避孕套使用。改善抑郁症的诊断和治疗有助于预防艾滋病毒。
We examined the effect of antiretroviral therapy (ART), and the predictive role of depression, on condom use with primary partners. Data from three studies in Uganda were combined into a sample of 750 patients with a primary sex partner, with 502 starting ART and 248 entering HIV care, and followed for 12 months. Random-effects logistic regression models were used to examine the impact of ART, and the influence of baseline level and change in depression, on condom use with primary partners. At Month 12, 61% ART and 67% non-ART patients were consistent condom users, compared to 44% and 41% at baseline, respectively. Multivariate analysis revealed that consistent condom use increased similarly for ART and non-ART patients, and that Minor Depression at baseline and increased depression over time predicted inconsistent condom use. Improved depression diagnosis and treatment could benefit HIV prevention.
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