Calcific Uremic Arteriolopathy: A Case Series and Review from an Inner-City Tertiary University Center in End-Stage Renal Disease Patients on Renal Replacement Therapy.
Calcific Uremic Arteriolopathy: A Case Series and Review from an Inner-City Tertiary University Center in End-Stage Renal Disease Patients on Renal Replacement Therapy.
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DOI：
10.1155/2021/6661042
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发表时间：
2021
影响因子：
2.1
通讯作者：
Osman-Malik Y
中科院分区：
文献类型：
--
作者：
Omer M;Bhat ZY;Fonte N;Imran N;Sondheimer J;Osman-Malik Y
2007年至2016年，在底特律医学中心对24例接受RRT的CUA患者进行了评价。几乎所有的患者都进行了皮肤活检，沿着放射学和临床表现。从电子病历中检索患者的临床和临床旁数据。使用适当的统计学检验将治疗方式和基础甲状旁腺功能亢进管理的效果与临床结局进行比较。 21名患者接受血液透析，2名患者接受肾移植，1名患者接受腹膜透析。糖尿病是终末期肾病最常见的病因。22例患者甲状旁腺激素（PTH）水平升高。15例患者在皮肤病变发作前2周或更长时间被诊断。22例和13例患者分别接受硫代硫酸钠和西那卡塞治疗。PTH和钙磷乘积水平较低的患者CUA的结局相对较好。 多方面的方法可能在治疗CUA中发挥作用。转诊给肾脏科医生可能有助于早期诊断和及时治疗CUA。
24 patients with CUA and on RRT were evaluated at Detroit Medical Center from 2007 to 2016. Skin biopsy was used in almost all patients, along with the radiological and clinical findings. The patient's clinical and paraclinical data were retrieved from the electronic medical records. The effect of treatment modalities and the underlying hyperparathyroidism management were compared to the clinical outcomes using appropriate statistical tests. Twenty-one patients were on hemodialysis, two patients received renal transplants, and one patient was on peritoneal dialysis. Diabetes mellitus was the most prevalent cause of ESRD. The parathyroid hormone level (PTH) was elevated in 22 patients. Fifteen patients were diagnosed 2 weeks or more prior to skin lesion onset. Twenty-two and thirteen patients received sodium thiosulphate and cinacalcet, respectively. Patients with lower PTH and the calcium-phosphate product levels had a relatively better outcome of CUA. A multifaceted approach may play a role in treating CUA. Referral to a nephrologist may aid in the early diagnosis and prompt management of CUA.
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DOI：
10.1053/j.ajkd.2015.01.034
发表时间：
2015-07
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Nigwekar SU;Kroshinsky D;Nazarian RM;Goverman J;Malhotra R;Jackson VA;Kamdar MM;Steele DJ;Thadhani RI
通讯作者：
Thadhani RI
影响因子：
13.8
作者：
Halasz, Charles L.;Munger, David P.;Wainwright, Sandra
通讯作者：
Wainwright, Sandra
影响因子：
13.2
作者：
Ahmed, S;O'Neill, KD;Moe, SM
通讯作者：
Moe, SM
影响因子：
13.8
作者：
Amuluru, Lavanya;High, Whitney;Hiatt, Kim M.;Ranville, James;Shah, Sudhir V.;Malik, Bilal;Swaminathan, Sundararaman
通讯作者：
Swaminathan, Sundararaman
DOI：
10.1016/0190-9622(95)90286-4
发表时间：
1995-12-01
影响因子：
13.8
作者：
HAFNER, J;KEUSCH, G;BURG, G
通讯作者：
BURG, G