The association of obesity and cervical cancer screening: a systematic review and meta-analysis.
The association of obesity and cervical cancer screening: a systematic review and meta-analysis.
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DOI：
10.1038/oby.2008.480
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发表时间：
2009-02
期刊：
影响因子：
6.9
通讯作者：
Clark, Jeanne M.
中科院分区：
文献类型：
--
作者：
Maruthur, Nisa M.;Bolen, Shari D.;Brancati, Frederick L.;Clark, Jeanne M.
肥胖妇女死于宫颈癌的风险增加，但对此的解释尚不清楚。通过我们的系统回顾，我们试图确定肥胖是否与宫颈癌筛查相关，以及这种关联是否因种族而异。我们通过电子（PubMed、CINAHL和科克伦图书馆）和手动检索，在美国识别出评价体重与巴氏试验之间关系的原始文章。我们排除了特殊人群的研究或那些不是用英语写的研究。两名评审员依次提取研究数据，并使用标准化表格独立提取质量。4，132篇引文产生了11项相关研究。10项研究表明肥胖和宫颈癌筛查之间存在负相关。与BMI正常的女性相比，巴氏试验的合并优势比（95%CI）分别为0.91（0.80至1.03）、0.81（0.70至0.93）、0.75（0.64至0.88）和0.62（0.55至0.69）。4项研究中有3项按种族列出了结果，发现这对白色女性是正确的，但没有研究发现这对黑人女性是正确的。总之，肥胖女性比瘦女性更不可能报告接受宫颈癌筛查，这对黑人女性来说并不成立。较少的筛查可能部分解释了肥胖白色妇女宫颈癌死亡率较高的原因。
Obese women are at an increased risk of death from cervical cancer, but the explanation for this is unknown. Through our systematic review, we sought to determine whether obesity is associated with cervical cancer screening and if this association differs by race. We identified original articles evaluating the relationship between body weight and Papanicolaou testing in the United States through electronic (PubMed, CINAHL, and the Cochrane Library) and manual searching. We excluded studies in special populations or those not written in English. Two reviewers sequentially extracted study data and independently extracted quality using standardized forms. 4,132 citations yielded 11 relevant studies. Ten studies suggested an inverse association between obesity and cervical cancer screening. Compared to women with a normal BMI, the combined odds ratios (95% CI) for Papanicolaou testing were 0.91 (0.80 to 1.03), 0.81 (0.70 to 0.93), 0.75 (0.64 to 0.88), and 0.62 (0.55 to 0.69) for the overweight and class I, class II, and class III obesity categories, respectively. Three of 4 studies that presented the results by race found this held true for white women, but no study found this for black women. In conclusion, obese women are less likely to report being screened for cervical cancer than their lean counterparts, and this does not hold true for black women. Less screening may partly explain the higher cervical cancer mortality seen in obese white women.
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影响因子：
7.1
作者：
ROWLAND, ML
通讯作者：
ROWLAND, ML
影响因子：
6.2
作者：
Lacey, JV;Swanson, CA;Hildesheim, A
通讯作者：
Hildesheim, A
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
1.6
作者：
ADAMS, CH;SMITH, NJ;GRADY, KE
通讯作者：
GRADY, KE
影响因子：
158.5
作者：
Calle, EE;Rodriguez, C;Thun, MJ
通讯作者：
Thun, MJ