An expanding universe of mRNA modifications.
An expanding universe of mRNA modifications.
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DOI:
10.1038/nsmb.2911
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发表时间:
2014-11
影响因子:
16.8
通讯作者:
Jaffrey SR
中科院分区:
文献类型:
--
作者:
Jaffrey SR
The fate of mRNA can be regulated by internal base modifications, with the currently known modified bases being N6-methyladenosine, 5-methylcytosine, and inosine. Three new studies show that yeast and human mRNA also contain pseudouridine residues and that pseudouridylation is induced in various stress states, hinting at a new pathway for post-transcriptional control of mRNA.
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