InterPro in 2011: new developments in the family and domain prediction database.

InterPro in 2011: new developments in the family and domain prediction database.
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DOI:
10.1093/nar/gkr948
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发表时间:
2012-01
影响因子:
14.9
通讯作者:
Yong SY
Yong SY
中科院分区:
生物学2区
文献类型:
--
作者:
Hunter S;Jones P;Mitchell A;Apweiler R;Attwood TK;Bateman A;Bernard T;Binns D;Bork P;Burge S;de Castro E;Coggill P;Corbett M;Das U;Daugherty L;Duquenne L;Finn RD;Fraser M;Gough J;Haft D;Hulo N;Kahn D;Kelly E;Letunic I;Lonsdale D;Lopez R;Madera M;Maslen J;McAnulla C;McDowall J;McMenamin C;Mi H;Mutowo-Muellenet P;Mulder N;Natale D;Orengo C;Pesseat S;Punta M;Quinn AF;Rivoire C;Sangrador-Vegas A;Selengut JD;Sigrist CJ;Scheremetjew M;Tate J;Thimmajanarthanan M;Thomas PD;Wu CH;Yeats C;Yong SY

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InterPro(http://www.ebi.ac.uk/interpro/)是一个数据库,它整合了关于蛋白质家族、结构域和功能位点的各种信息,并通过基于Web的界面和服务向公众免费提供。该数据库的核心是诊断模型,称为签名,可以搜索蛋白质序列以确定其潜在功能。InterPro可用于大规模分析全基因组和元基因组,以及表征单个蛋白质序列。在此,我们概述了自2009年以来数据库及其相关软件的新发展,包括数据库内容、策展流程以及Web和编程接口的更新。
InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has utility in the large-scale analysis of whole genomes and meta-genomes, as well as in characterizing individual protein sequences. Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces.
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