Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus.

Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus.
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DOI:
10.1038/sdata.2016.75
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发表时间:
2016-09-13
期刊:
影响因子:
9.8
通讯作者:
Tautz, Diethard
Tautz, Diethard
中科院分区:
综合性期刊2区
文献类型:
--
作者:
Harr, Bettina;Karakoc, Emre;Neme, Rafik;Teschke, Meike;Pfeifle, Christine;Pezer, Zeljka;Babiker, Hiba;Linnenbrink, Miriam;Montero, Inka;Scavetta, Rick;Abai, Mohammad Reza;Puente Molins, Marta;Schlegel, Mathias;Ulrich, Rainer G.;Altmueller, Janine;Franitza, Marek;Buentge, Anna;Kuenzel, Sven;Tautz, Diethard

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家鼠(Mus musculus)的野生种群代表了生物医学研究中经典近交系的原始遗传材料,并且是进化生物学的主要模型系统。我们提供了代表M自然种群的个体全基因组测序数据。M. 3个种群的24个个体; M. helgolandicus(3个个体),M. M. musculus(3个种群22只)和M. spretus(一个种群8个个体)。我们使用单个管道来映射和调用这些个体的变体,还包括另外10个M个体。M.其基因组数据在实验上是可获得的。此外,RNAseq数据是从三个M中的每一个的多达八个成年个体的10个组织中获得的。M.收集了其基因组数据。数据和分析通过UCSC或IGV基因组浏览器中可见的轨迹呈现。我们还提供了关于可用的远系繁殖的股票和如何在实验室保持他们的指示信息。
Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. We provide whole genome sequencing data of individuals representing natural populations of M. m. domesticus (24 individuals from 3 populations), M. m. helgolandicus (3 individuals), M. m. musculus (22 individuals from 3 populations) and M. spretus (8 individuals from one population). We use a single pipeline to map and call variants for these individuals and also include 10 additional individuals of M. m. castaneus for which genomic data are publically available. In addition, RNAseq data were obtained from 10 tissues of up to eight adult individuals from each of the three M. m. domesticus populations for which genomic data were collected. Data and analyses are presented via tracks viewable in the UCSC or IGV genome browsers. We also provide information on available outbred stocks and instructions on how to keep them in the laboratory.
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