Cardiac magnetic resonance fingerprinting: Trends in technical development and potential clinical applications.

Cardiac magnetic resonance fingerprinting: Trends in technical development and potential clinical applications.
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心脏磁共振指纹技术:技术发展趋势及潜在临床应用

DOI:
10.1016/j.pnmrs.2020.10.001
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发表时间:
2021-03
影响因子:
6.1
通讯作者:
Seiberlich N
Seiberlich N
中科院分区:
化学1区
文献类型:
--
作者:
Eck BL;Flamm SD;Kwon DH;Tang WHW;Vasquez CP;Seiberlich N

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近年来,定量心脏磁共振已成为评估一系列心血管疾病的一种方法,其中T1和T2 mapping处于这些发展的前沿。心脏磁共振指纹成像(cMRF)为同时定量心肌T1和T2以及其他组织特性提供了一个快速且稳健的框架。自cMRF出现以来,已有许多技术发展和临床验证研究的报道。本综述概述了cMRF、近期技术发展、健康受试者和患者研究、预期的技术改进以及潜在的临床应用。近期技术发展包括层面轮廓和脉冲效率校正、图像重建的改进、同时多层成像、3D全心室成像、运动分辨成像、脂肪 - 水分离以及用于快速生成字典的机器学习。还描述了cMRF未来的技术发展,如B0和B1场映射、采集和重建的加速、植入设备患者的成像以及其他组织特性的定量。潜在临床应用包括浸润性、炎症性和缺血性心肌病的特征描述、左心房和右心室的组织特征描述、心脏移植术后评估、造影剂的减少、电生理干预的术前规划以及植入设备患者的成像。
Quantitative cardiac magnetic resonance has emerged in recent years as an approach for evaluating a range of cardiovascular conditions, with T1 and T2 mapping at the forefront of these developments. Cardiac Magnetic Resonance Fingerprinting (cMRF) provides a rapid and robust framework for simultaneous quantification of myocardial T1 and T2 in addition to other tissue properties. Since the advent of cMRF, a number of technical developments and clinical validation studies have been reported. This review provides an overview of cMRF, recent technical developments, healthy subject and patient studies, anticipated technical improvements, and potential clinical applications. Recent technical developments include slice profile and pulse efficiency corrections, improvements in image reconstruction, simultaneous multislice imaging, 3D whole-ventricle imaging, motion-resolved imaging, fat-water separation, and machine learning for rapid dictionary generation. Future technical developments in cMRF, such as B0 and B1 field mapping, acceleration of acquisition and reconstruction, imaging of patients with implanted devices, and quantification of additional tissue properties are also described. Potential clinical applications include characterization of infiltrative, inflammatory, and ischemic cardiomyopathies, tissue characterization in the left atrium and right ventricle, post-cardiac transplantation assessment, reduction of contrast material, pre-procedural planning for electrophysiology interventions, and imaging of patients with implanted devices.
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