Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study.
Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study.
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DOI：
10.1186/s12889-020-09719-w
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发表时间：
2020-11-05
影响因子：
4.5
通讯作者：
Wang L
中科院分区：
文献类型：
--
作者：
Jia L;Liu Q;Hou H;Guo G;Zhang T;Fan S;Wang L
环境空气污染正在成为中国的一个严重的环境问题。关于空气污染是妊娠期先兆子痫的危险因素，结果不一致。中国，2015年1月1日至2017年12月31日，来自河北省10个市22家医院的孕妇共116,042人。将产妇分为先兆子痫组(PE组)和非先兆子痫组(非PE组)。大气污染物颗粒物(PM2.5)、可吸入颗粒物(PM10)、亚硝酸盐(NO2)、二氧化硫(SO2)、一氧化碳(CO)、臭氧(O3)等大气污染物数据来自中国环境监测站。在116,042名孕妇中，2988名(2.57%)被诊断为先兆子痫。早孕组暴露PM2.5、PM10、NO2、O3浓度均显著高于非早孕组，分别为早孕期和孕中期的危险因素。暴露SO2和CO浓度在孕中期与非孕期妇女无差异，但高浓度是孕中期发生孕期肺损伤的危险因素。孕早、中期暴露PM2.5、PM10、NO2、O3是子痫前期的危险因素，而SO2、CO只有在孕中期高水平暴露才是子痫前期的危险因素。
Ambient air pollution is becoming a serious environmental problem in China. The results were inconsistent on that air pollution was a risk factor of preeclampsia in pregnancy. Total 116,042 pregnant women were enrolled from 22 hospitals in 10 cities of Hebei Province, China from January 1, 2015 to December 31, 2017. The parturients were divided into preeclampsia group (PE group) and non-preeclampsia group (non-PE group). The data of air pollutants, namely, particulate matter (PM)2.5, PM10, NO2, SO2, CO, O3 were collected from China Environmental Inspection Station. Among the 116,042 pregnant women, 2988 (2.57%) pregnant women were diagnosed with preeclampsia. The concentrations of exposed PM2.5, PM10, NO2 and O3 in the PE group were significantly higher than those in the non-PE group, and they were risk factors of the PE group in the first and second trimester of pregnancy respectively. The concentrations of exposed SO2 and CO in PE patients and non-PE women were not different, but high concentration of these air pollutants were risk factors to PE in the second trimester. The exposure to PM2.5, PM10, NO2, O3 were risk factors for preeclampsia in the first and second trimester of pregnancy, while only at high level, SO2 and CO were risk factors for preeclampsia in the second trimester of pregnancy.
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DOI：
10.1136/bmj.f6564
发表时间：
2013-11-07
期刊：
BMJ (Clinical research ed.)
影响因子：
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作者：
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影响因子：
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作者：
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