Nonlinear and nonlocal elasticity in coarse-grained differential-tension models of epithelia
Nonlinear and nonlocal elasticity in coarse-grained differential-tension models of epithelia
复制标题
上皮细胞粗粒度差分张力模型中的非线性和非局部弹性
DOI：
10.1101/449694
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Goldstein Raymond E.
中科院分区：
文献类型：
--
作者：
Haas Pierre A.;Goldstein Raymond E.
The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning different surface tensions to the apical, basal, and lateral sides of the cells. These differential-tension models have been used to describe the deformations of epithelia in different living systems, but the underlying continuum mechanics at the scale of the epithelium are still unclear. Here, we derive a continuum theory for a simple differential-tension model of a two-dimensional epithelium and study the buckling of this epithelium under imposed compression. The analysis reveals howthe cell-level properties encoded in the differential-tension model lead to linear, nonlinear as well as nonlocal elastic behavior at the continuum level.
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影响因子：
12.5
作者：
Bi, Dapeng;Yang, Xingbo;Manning, M. Lisa
通讯作者：
Manning, M. Lisa
DOI：
--
发表时间：
--
期刊：
--
影响因子：
--
作者：
通讯作者：
--
影响因子：
5.3
作者：
Mihai, L. Angela;Budday, Silvia;Goriely, Alain
通讯作者：
Goriely, Alain
影响因子：
9.7
作者：
Budday, S.;Sommer, G.;Holzapfel, G. A.
通讯作者：
Holzapfel, G. A.