The ion funnel: theory, implementations, and applications.

The ion funnel: theory, implementations, and applications.
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DOI:
10.1002/mas.20232
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发表时间:
2010-03
影响因子:
6.6
通讯作者:
Smith, Richard D.
Smith, Richard D.
中科院分区:
化学2区
文献类型:
--
作者:
Kelly, Ryan T.;Tolmachev, Aleksey V.;Page, Jason S.;Tang, Keqi;Smith, Richard D.

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电动离子漏斗使得能够在挑战传统方法的压力范围(0.1至30托)中操纵和聚焦离子,为更大的质谱仪离子传输效率提供了基础。最初的离子漏斗实施方式旨在有效地捕获电喷雾电离源的膨胀气体射流中的离子,并径向地聚焦它们以通过电导限制孔进行有效的转移。我们回顾了离子漏斗中的离子运动的基本理解的改进,在其实现的演变,带来了离子漏斗,其目前的状态的细化,以及应用的离子漏斗的目的,如离子捕获,离子冷却,低压电喷雾,和离子迁移率光谱。
The electrodynamic ion funnel has enabled the manipulation and focusing of ions in a pressure regime (0.1 to 30 Torr) that has challenged traditional approaches, providing the basis for much greater mass spectrometer ion transmission efficiencies. The initial ion funnel implementations aimed to efficiently capture ions in the expanding gas jet of an electrospray ionization source and radially focus them for efficient transfer through a conductance limiting orifice. We review the improvements in fundamental understanding of ion motion in ion funnels, the evolution in its implementations that have brought the ion funnel to its current state of refinement, as well as applications of the ion funnel for purposes such as ion trapping, ion cooling, low pressure electrospray, and ion mobility spectrometry.
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