Economic analysis of early intervention for autistic children: findings from four case studies in England, Ireland, Italy, and Spain.
Economic analysis of early intervention for autistic children: findings from four case studies in England, Ireland, Italy, and Spain.
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自闭症儿童早期干预的经济分析：英格兰、爱尔兰、意大利和西班牙四个案例研究的结果。
DOI：
10.1192/j.eurpsy.2023.2449
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发表时间：
2023-09-21
影响因子：
7.8
通讯作者：
Quoidbach, Vinciane
中科院分区：
文献类型：
--
作者：
Tinelli, Michela;Roddy, Aine;Knapp, Martin;Arango, Celso;Mendez, Maria Andreina;Cusack, James;Murphy, Declan;Canitano, Roberto;Oakley, Bethany;Quoidbach, Vinciane
许多自闭症儿童在沟通和语言技能发展方面遇到困难，对成年后的社会发展造成影响，往往导致生命过程中的挑战，并对个人、家庭和社会造成巨大的经济影响。学龄前自闭症沟通试验(PACT)干预在改善社会沟通和一些次要结果方面是有效的。之前发表的一项试验内经济分析发现，13个月的结果不支持其成本效益。我们在6年内对四个欧洲国家的成本效益进行了建模。使用模拟建模，我们在最初的试验中进行了经济分析，探索了(英国)6年后的长期成本效益。我们调整了我们的模型，对爱尔兰、意大利和西班牙的协定进行了经济分析。有关资源使用的数据来自最初的试验和爱尔兰最近的一项观察性研究。从社会角度来看，PACT随着时间的推移是节省成本的，尽管我们证实，在分娩后13个月，PACT对学龄前自闭症儿童的治疗(在所有国家)都比通常的治疗更昂贵。6年后，我们发现，就父母提供的无偿护理而言，PACT比通常的治疗成本更低(在所有国家)。此外，如果我们只考虑爱尔兰研究的自付费用，PACT的成本比通常的治疗要低。对于患有自闭症儿童的家庭，PACT可能被推荐为一种节省成本的早期干预措施。
Many autistic children experience difficulties in their communication and language skills development, with consequences for social development into adulthood, often resulting in challenges over the life-course and high economic impacts for individuals, families, and society. The Preschool Autism Communication Trial (PACT) intervention is effective in terms of improved social communication and some secondary outcomes. A previously published within-trial economic analysis found that results at 13 months did not support its cost-effectiveness. We modeled cost-effectiveness over 6 years and across four European countries. Using simulation modeling, we built on economic analyses in the original trial, exploring longer-term cost-effectiveness at 6 years (in England). We adapted our model to undertake an economic analysis of PACT in Ireland, Italy, and Spain. Data on resource use were taken from the original trial and a more recent Irish observational study. PACT is cost-saving over time from a societal perspective, even though we confirmed that, at 13 months post-delivery, PACT is more expensive than usual treatment (across all countries) when given to preschool autistic children. After 6 years, we found that PACT has lower costs than usual treatment in terms of unpaid care provided by parents (in all countries). Also, if we consider only out-of-pocket expenses from an Irish study, PACT costs less than usual treatment. PACT may be recommended as a cost-saving early intervention for families with an autistic child.
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影响因子：
3.9
作者：
Leadbitter K;Aldred C;McConachie H;Le Couteur A;Kapadia D;Charman T;Macdonald W;Salomone E;Emsley R;Green J;PACT Consortium
通讯作者：
PACT Consortium
影响因子：
3.3
作者：
Roddy, Aine;O'Neill, Ciaran
通讯作者：
O'Neill, Ciaran
影响因子：
4.4
作者：
Bojke, Laura;Manca, Andrea;Palmer, Stephen
通讯作者：
Palmer, Stephen
影响因子：
168.9
作者：
Green, Jonathan;Charman, Tony;Pickles, Andrew
通讯作者：
Pickles, Andrew
DOI：
10.1177/1362361320936394
发表时间：
2020-11
期刊：
Autism : the international journal of research and practice
影响因子：
--
作者：
Leadbitter K;Macdonald W;Taylor C;Buckle KL;the PACT Consortium*
通讯作者：
the PACT Consortium*