Structure of ferredoxin-NADP oxidoreductase and the location on the NADP binding site. Results at 3-7 A resolution.
Structure of ferredoxin-NADP oxidoreductase and the location on the NADP binding site. Results at 3-7 A resolution.
复制标题
铁氧还蛋白-NADP 氧化还原酶的结构和 NADP 结合位点的位置。
DOI：
10.1016/0022-2836(81)90214-x
复制
发表时间：
1981
影响因子：
5.6
通讯作者：
Herriott,JR
中科院分区：
文献类型：
--
作者：
Sheriff,S;Herriott,JR
铁氧还蛋白-NADP+氧化还原酶是负责在光合作用期间催化NADPH产生的酶。用反常散射多重同晶置换法，在3.7 μ m分辨率下确定了铁氧还蛋白还原酶的结构。该分子由两个结构域组成，正如预期的结合两个核苷酸，FAD和NADP的酶。NADP结合位点已被定位的差分傅立叶图的手段。这种辅酶结合在四链平行折叠片的第一链的羧基端，靠近几个相邻螺旋的氨基端。结合出现类似的烟酰胺核苷酸在其他protein.We报告在这里的整体描述的分子的形状，折叠的多肽链在NADP结合域和NADP结合位点的位置的初步解释。
Ferredoxin-NADP+oxidoreductase is the enzyme responsible for catalyzing the production of NADPH during photosynthesis. The structure of “ferredoxin reductase” has been elucidated at 3.7 Å resolution by the method of multiple isomorphous replacement with anomalous scattering. The molecule consists of two structural domains, as anticipated for an enzyme that binds two nucleotides, FAD and NADP.The NADP binding site has been located by means of a difference Fourier map. This coenzyme binds at the carboxyl end of the first strand of a four-strand parallel pleated sheet near the amino end of several adjacent helices. The binding appears similar to that of nicotinamide nucleotides in other proteins.We report here an overall description of the shape of the molecule, a preliminary interpretation of the folding of the polypeptide chain in the NADP binding domain and the location of the NADP binding site.
登录
查看更多内容
来自干酪乳杆菌的二氢叶酸还原酶。
DOI：
10.1016/s0021-9258(18)50708-0
发表时间：
1979
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
D. Matthews;R. A. Alden;S. Freer;N. Xuong;J. Kraut
通讯作者：
J. Kraut
影响因子：
3.9
作者：
D. Davis;A. San Pietro
通讯作者：
A. San Pietro
蛋白质衍生物中重原子位置的测定
DOI：
10.1107/s0365110x66002731
发表时间：
1966
期刊：
Acta Crystallographica
影响因子：
--
作者：
A. K. Singh;S. Ramaseshan
通讯作者：
S. Ramaseshan
菠菜叶中铁氧还蛋白、铁氧还蛋白-NADP还原酶和质体蓝素的联合制备。
DOI：
10.1016/0005-2728(70)90010-1
发表时间：
1970
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
M. Borchert;J. Wessels
通讯作者：
J. Wessels
影响因子：
64.8
作者：
SCHULZ, GE;SCHIRMER, RH;PAI, EF
通讯作者：
PAI, EF