Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review.
Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review.
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DOI：
10.3390/nu14050982
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发表时间：
2022-02-25
期刊：
影响因子：
5.9
通讯作者：
Migliario M
中科院分区：
文献类型：
--
作者：
de Sire A;Ferrillo M;Lippi L;Agostini F;de Sire R;Ferrara PE;Raguso G;Riso S;Roccuzzo A;Ronconi G;Invernizzi M;Migliario M
虚弱是老年人中非常普遍的一种状况，由于与脆性骨折、住院和死亡的高风险密切相关，它已日益被视为一个重要的公共卫生问题。在与年龄相关的疾病中，肌肉减少症和吞咽困难是虚弱的老年人常见的两种病理状态，它们可能并存，导致老年人脱水和营养不良。“肌肉减少性吞咽困难”是一种复杂的疾病，其特征是吞咽肌肉质量和力量的丧失导致吞咽功能受损，也可能与口腔健康状况不佳有关。此外，由于免疫系统和伤口愈合的直接损害，衰老过程与口腔健康状况不佳密切相关，身体和认知障碍可能间接影响老年人进行充分口腔卫生的能力。因此，口腔健康状况不佳可能影响营养摄入，导致营养不良，从而导致身体虚弱。在这种情况下，肌肉减少症、吞咽困难和口腔健康密切相关，共享共同的病理生理途径、致残后遗症和虚弱。因此，本综合综述的目的是描述肌肉减少性吞咽困难、营养不良和口腔虚弱之间的相关性，描述它们的表型重叠特征，提出全面有效的老年虚弱受试者管理方法。
Frailty is a highly prevalent condition in the elderly that has been increasingly considered as a crucial public health issue, due to the strict correlation with a higher risk of fragility fractures, hospitalization, and mortality. Among the age-related diseases, sarcopenia and dysphagia are two common pathological conditions in frail older people and could coexist leading to dehydration and malnutrition in these subjects. “Sarcopenic dysphagia” is a complex condition characterized by deglutition impairment due to the loss of mass and strength of swallowing muscles and might be also related to poor oral health status. Moreover, the aging process is strictly related to poor oral health status due to direct impairment of the immune system and wound healing and physical and cognitive impairment might indirectly influence older people’s ability to carry out adequate oral hygiene. Therefore, poor oral health might affect nutrient intake, leading to malnutrition and, consequently, to frailty. In this scenario, sarcopenia, dysphagia, and oral health are closely linked sharing common pathophysiological pathways, disabling sequelae, and frailty. Thus, the aim of the present comprehensive review is to describe the correlation among sarcopenic dysphagia, malnutrition, and oral frailty, characterizing their phenotypically overlapping features, to propose a comprehensive and effective management of elderly frail subjects.
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DOI：
10.1111/j.1532-5415.2011.03502.x
发表时间：
2011-08-01
影响因子：
6.3
作者：
Avlund, Kirsten;Schultz-Larsen, Kirsten;Holm-Pedersen, Poul
通讯作者：
Holm-Pedersen, Poul
影响因子：
1.4
作者：
Belafsky, Peter C.;Mouadeb, Debbie A.;Leonard, Rebecca J.
通讯作者：
Leonard, Rebecca J.
影响因子：
3.5
作者：
Ameri, Ahmad;Heydarirad, Ghazaleh;Gachkar, Latif
通讯作者：
Gachkar, Latif
影响因子：
4.3
作者：
Aimetti, Mario;Romano, Federica;Nessi, Franco
通讯作者：
Nessi, Franco
影响因子：
1
作者：
Alghadir, Ahmad H.;Zafar, Hamayun;Iqbal, Zaheen A.
通讯作者：
Iqbal, Zaheen A.