Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor.
Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor.
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DOI:
10.1039/c3cc00173c
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发表时间:
2014-03-21
期刊:
影响因子:
--
通讯作者:
Disney MD
中科院分区:
文献类型:
--
作者:
Velagapudi SP;Disney MD
The RNA motifs that bind guanidinylated kanamycin A (G Kan A) and guanidinylated neomycin B (G Neo B) were identified via two-dimensional combinatorial screening (2DCS). The results of these studies enabled the “bottom-up” design of a small molecule inhibitor of oncogenic microRNA-10b.
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DOI:
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通讯作者:
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