Cognitive control dysfunction in workers exposed to manganese-containing welding fume.
Cognitive control dysfunction in workers exposed to manganese-containing welding fume.
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DOI：
10.1002/ajim.22675
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发表时间：
2017-03
影响因子：
3.5
通讯作者：
Racette BA
中科院分区：
文献类型：
--
作者：
Al-Lozi A;Nielsen SS;Hershey T;Birke A;Checkoway H;Criswell SR;Racette BA
在焊接等职业中，长期接触锰是一个健康问题，因为由于基底节功能障碍，运动效应已经确立。我们假设，认知控制(监控、操纵和调节正在进行的认知需求的能力)也会受到慢性锰暴露的影响。我们调查了95名不同强度和接触焊接烟尘时间(中位数15.5年)的工人的锰暴露与认知控制能力之间的关系。我们通过线性回归来评估接触含锰焊接烟尘与认知控制任务之间的关系。总体表现与焊接暴露强度呈负相关(p=0.009)，并由评估工作记忆的双背和字母数字排序测试驱动(p=0.02)。职业性接触含锰焊接烟雾可能与较差的工作记忆表现有关，工人可能从降低暴露强度的做法中受益。
Chronic exposure to manganese (Mn) is a health concern in occupations such as welding because of well-established motor effects due to basal ganglia dysfunction. We hypothesized that cognitive control (the ability to monitor, manipulate, and regulate ongoing cognitive demands) would also be affected by chronic Mn exposure. We examined the relationship between Mn exposure and cognitive control performance in 95 workers with varying intensity and duration (median 15.5 years) of exposure to welding fume. We performed linear regression to assess the association between exposure to Mn-containing welding fume and cognitive control tasks. Overall performance was inversely related to intensity of welding exposure (p=0.009) and was driven by the Two-Back and Letter Number Sequencing tests that assess working memory (both p=0.02). Occupational exposure to Mn-containing welding fume may be associated with poorer working memory performance, and workers may benefit from practices that reduce exposure intensity.
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影响因子：
2
作者：
Hobson AJ;Sterling DA;Emo B;Evanoff BA;Sterling CS;Good L;Seixas N;Checkoway H;Racette BA
通讯作者：
Racette BA
影响因子：
2
作者：
Baker MG;Simpson CD;Stover B;Sheppard L;Checkoway H;Racette BA;Seixas NS
通讯作者：
Seixas NS
影响因子：
5.7
作者：
Mikos, A;Bowers, D;Noecker, A M;McIntyre, C C;Won, M;Chaturvedi, A;Foote, K D;Okun, M S
通讯作者：
Okun, M S
影响因子：
3.2
作者：
Wylie SA;Ridderinkhof KR;Bashore TR;van den Wildenberg WP
通讯作者：
van den Wildenberg WP
影响因子：
3.4
作者：
Ellingsen, Dag G.;Konstantinov, Roman;Chashchin, Valery
通讯作者：
Chashchin, Valery