Repairing boundaries along pathways to tuberculosis case detection: a qualitative synthesis of intervention designs.

Repairing boundaries along pathways to tuberculosis case detection: a qualitative synthesis of intervention designs.
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DOI:
10.1186/s12961-021-00811-0
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发表时间:
2022-01-10
影响因子:
4
通讯作者:
Oliver S
Oliver S
中科院分区:
医学2区
文献类型:
--
作者:
van Wyk SS;Medley N;Young T;Oliver S

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结核病病例发现干预措施通常涉及几项活动,以加强患者途径,目前尚不清楚哪种活动定义了病例发现干预措施的类型。在开展研究以确定最有效的病例发现干预措施时,重要的是要清楚地了解这些干预措施,以便进行有意义的比较。本综述旨在通过综合干预设计,构建一个基于系统的结核病病例检测所有途径的逻辑模型。我们确定了一项现有的关于增加结核病病例检出率的干预措施有效性的系统综述,并更新了2016年12月至2020年10月的研究。我们纳入了随机对照试验,因为这些设计鼓励对干预措施进行详细描述。依次对每项研究进行详细的干预描述。通过不断比较新出现的代码,对文本进行定性分析,以构建患者旅程,可视化为逻辑链。作为干预措施的一部分,所采取的行动被定位在患者旅程中,以理论化结果的顺序。病人的旅程形成了模型的基础,并通过讨论加以完善。基于17个随机对照试验的干预描述,我们的模型区分了两种求医途径和四种筛查途径。对有肺结核症状的人的公开邀请创造了求医途径。关于求医途径,可在一般卫生服务机构进行系统筛查,但不能在特定结核病保健服务机构进行。被邀请接受结核病服务的人,无论症状如何,都遵循结核病筛查途径,即使他们没有因结核病症状寻求治疗,也可能被确诊为结核病。结核病筛查途径包括向所有在一般卫生服务机构获得护理的人提供筛查,在流动诊所或卫生设施公开邀请对全体人口或结核病接触者进行筛查,向全体人口或家庭、工作场所或学校的结核病接触者亲自提供筛查,以及向接受人类免疫缺陷病毒护理或其他临床风险群体护理的人提供筛查。这种基于系统的结核病病例发现途径逻辑模型可以在实施和评估改善结核病病例发现的干预措施时支持标准化术语、一致性、透明度和改善研究人员、决策者、卫生工作者和社区成员之间的沟通。在线版本包含补充材料,可在10.1186/s12961-021-00811-0获得。
Tuberculosis case-finding interventions often involve several activities to enhance patient pathways, and it is unclear which activity defines the type of case-finding intervention. When conducting studies to identify the most effective case-finding intervention it is important to have a clear understanding of these interventions for meaningful comparisons. This review aimed to construct a systems-based logic model of all pathways to tuberculosis case detection through a synthesis of intervention designs. We identified an existing systematic review on the effectiveness of interventions to increase tuberculosis case detection and updated the search from December 2016 to October 2020. We included randomized controlled trials, as these designs encourage detailed description of interventions. Taking each study in turn, intervention descriptions were read in detail. The texts were analysed qualitatively by constantly comparing emerging codes to construct patient journeys, visualized as logical chains. Actions taken as part of interventions were positioned along patient journeys to theorize the sequence of outcomes. Patient journeys formed the basis of the model, which was refined through discussion. Based on intervention descriptions from 17 randomized controlled trials, our model distinguishes two care-seeking pathways and four screening pathways. An open invitation to people with tuberculosis symptoms creates care-seeking pathways. On care-seeking pathways, systematic screening can be conducted at general health services, but not at specific TB care services. People invited to tuberculosis services regardless of symptoms follow tuberculosis screening pathways and may be identified with presumptive tuberculosis even if they do not seek care for tuberculosis symptoms. Tuberculosis screening pathways include screening offered to all people accessing care at general health services, screening at a mobile clinic or health facility with open invitation to a whole population or tuberculosis contacts, screening personally offered to a whole population or tuberculosis contacts at home, work or school, and screening offered to people receiving care for human immunodeficiency virus or other clinical risk-group care. This systems-based logic model of tuberculosis case-finding pathways may support standardized terminology, consistency, transparency and improved communication among researchers, policy-makers, health workers and community members when implementing and evaluating interventions to improve tuberculosis case detection. The online version contains supplementary material available at 10.1186/s12961-021-00811-0.
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