A high prevalence of zinc- but not iron-deficiency among women in rural Malawi: a cross-sectional study.
A high prevalence of zinc- but not iron-deficiency among women in rural Malawi: a cross-sectional study.
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马拉维农村妇女缺锌但不缺铁的患病率很高：一项横断面研究。
DOI：
10.1024/0300-9831/a000158
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Siyame EW
中科院分区：
文献类型：
--
作者：
Siyame EW
背景：锌缺乏通常与营养性铁缺乏（ID）有关，并且可能因低硒状态而加剧。目的：探讨不同硒水平妇女铁锌缺乏的风险。方法：在一项横断面研究中，收集了来自低（Zombwe）（n= 60）和高植物有效土壤硒（Mikalango）（n= 60）地区的18 - 50岁马拉维妇女的1天膳食组合和血液样本。分析饮食中的微量元素和血液中的生物标志物。结果：锌缺乏症（bbb90 %）大于ID贫血（6%）或ID贫血（5%），归因于高植酸锌摩尔比（20.0）的低锌（中位5.7 mg/天）饮食，但高铁（21.0 mg/天）来自土壤污染物铁。与Mikalango女性相比，Zombwe女性的硒（6.5 vs. 55.3 μmol/ d）、锌（4.8 vs. 6.4 mg/d）、铁（16.6 vs. 29.6 mg/d）摄入量较低（p< 0.05），血浆硒含量较低（0.72 vs. 1.60 μmol/L），体铁含量较高（5.3 vs. 3.8 mg/kg），血浆锌含量相似（8.60 vs. 8.87 μmol/L）。体内铁和血浆锌是血红蛋白的阳性决定因素。结论：锌缺乏症的风险高于碘缺乏症，且与硒状态无关。作为血红蛋白的决定因素，血浆锌几乎和体内铁一样重要。
Background: Zinc deficiency is often associated with nutritional iron deficiency (ID), and may be exacerbated by low selenium status. Aim: To investigate risk of iron and zinc deficiency in women with contrasting selenium status. Methods: In a cross-sectional study, 1-day diet composites and blood samples were collected from self-selected Malawian women aged 18− 50 years from low-(Zombwe)(n= 60) and high-plant-available soil selenium (Mikalango)(n= 60) districts. Diets were analyzed for trace elements and blood for biomarkers. Results: Zinc deficiency (> 90%) was greater than ID anemia (6%), or ID (5%), attributed to diets low in zinc (median 5.7 mg/day) with high phytate: zinc molar ratios (20.0), but high in iron (21.0 mg/day) from soil contaminant iron. Zombwe compared to Mikalango women had lower (p< 0.05) intakes of selenium (6.5 vs. 55.3 μg/day), zinc (4.8 vs. 6.4 mg/day), iron (16.6 vs. 29.6 mg/day), lower plasma selenium (0.72 vs. 1.60 μmol/L), and higher body iron (5.3 vs. 3.8 mg/kg), although plasma zinc was similar (8.60 vs. 8.87 μmol/L). Body iron and plasma zinc were positive determinants of hemoglobin. Conclusion: Risk of zinc deficiency was higher than ID and was shown not to be associated with selenium status. Plasma zinc was almost as important as body iron as a hemoglobin determinant.
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DOI：
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发表时间：
2001
期刊：
--
影响因子：
--
作者：
J. Haas;Thomas Brownlie
通讯作者：
J. Haas;Thomas Brownlie
DOI：
10.1111/j.1471-0528.2001.00181.x
发表时间：
2001-07-01
期刊：
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
影响因子：
--
作者：
Merchant, KM;Villar, J;Kestler, E
通讯作者：
Kestler, E
蛋白激酶和磷酸酶参与促红细胞生成素介导的信号转导。
影响因子：
2.6
作者：
Spivak,JL;Fisher,J;Isaacs,MA;Hankins,WD
通讯作者：
Hankins,WD
发展中国家消费非食物来源的铁对铁状况的影响
影响因子：
3.2
作者：
Philip W.J. Harvey;Patricia B. Dexter;Ian Darnton
通讯作者：
Ian Darnton
铁储备低的年轻女性是否面临缺锌和缺铁的风险
DOI：
10.1007/0-306-47466-2_95
发表时间：
2002
期刊：
BJOG: An International Journal of Obstetrics & Gynaecology
影响因子：
--
作者：
R. Gibson;A. Heath;N. Prosser;W. Parnell;U. Donovan;Timothy J Green;K. Mclaughlin;D. O’Connor;W. Bettger;C. Skeaff
通讯作者：
C. Skeaff