Remembering past challenges to feel better today: Role of neural dedifferentiation and autobiographical integration in late-life reappraisal.
Remembering past challenges to feel better today: Role of neural dedifferentiation and autobiographical integration in late-life reappraisal.
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记住过去的挑战，以使今天感觉更好：神经去分化和自传整合在晚年重新评估中的作用。
DOI：
10.1080/13825585.2022.2044011
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发表时间：
2022-05
期刊：
影响因子：
--
通讯作者：
Heideman K
中科院分区：
文献类型：
--
作者：
Martins-Klein B;Orlovsky I;Heideman K
社会情绪理论认为，在一生的艰难生活经历中幸存下来可以增强老年人的情绪弹性，然而，在当前的情绪调节模型中，幸存过去的情绪挑战的作用被忽视了。年龄相关的神经去分化通常被认为是导致认知能力缺陷的原因，但在本文中，我们提出，随着年龄的增长，一般记忆和海马去分化的整合可能共同有利于对新压力源的重新评估。首先，我们回顾了经典的叙事心理学研究结果，这些研究结果支持越来越多的积极叙事和对晚年生活中不良事件的更多综合记忆对情绪的好处。其次，我们回顾了跨经验叙事整合的神经机制，包括通过重叠海马表征的意义制造和腹内侧前额叶皮层（vmPFC）的抽象意义表征。基于这些发现，我们提出了一个新的框架，说明叙事整合如何通过海马体对独特经历的表征的神经去分化，以及vmPFC在记忆中共享的积极叙事意义（重新评价），促进晚年生活中的重新评价。虽然目前支持该模型的证据有限，但我们最后讨论了在多变量神经影像学研究中测试其成分的未来方向，并简要回顾了所提出模型的临床意义。
Socioemotional theories suggest that surviving a lifetime of difficult life experiences enhances older adult emotional resilience, yet the role of surviving past emotional challenges in current models of emotion regulation is overlooked. Age-related neural dedifferentiation is often assumed to contribute to cognitive performance deficits, but in this paper, we propose that integration of overgeneral memories and hippocampal dedifferentiation with age may together benefit the reappraisal of novel stressors. First, we review classic narrative psychology findings supporting mood benefits from greater generation of positive narratives, and more integrated memories of adverse life events in later life. Second, we review the neural mechanisms of narrative integration across experiences, including meaning-making through overlapping hippocampal representations, and abstract meaning representations in the ventromedial prefrontal cortex (vmPFC). Based on these findings, we propose a novel framework of how narrative integration may facilitate reappraisal in later life through neural dedifferentiation of hippocampal representations for unique experiences, and shared positive narrative meaning across memories (reappraisals) in vmPFC. While current evidence supporting this model is limited, we conclude by discussing future directions for testing its components in multivariate neuroimaging studies, and briefly review clinical implications of the proposed model.
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影响因子：
3.8
作者：
Allard ES;Kensinger EA
通讯作者：
Kensinger EA
影响因子：
9.2
作者：
Cohn-Sheehy, Brendan, I;Delarazan, Angelique, I;Reagh, Zachariah M.;Crivelli-Decker, Jordan E.;Kim, Kamin;Barnett, Alexander J.;Zacks, Jeffrey M.;Ranganath, Charan
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作者：
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作者：
Bauer, Jack J.;McAdams, Dan P.
通讯作者：
McAdams, Dan P.
DOI：
10.1093/geronb/gbu108
发表时间：
2014-11-01
影响因子：
6.2
作者：
Allard, Eric S.;Kensinger, Elizabeth A.
通讯作者：
Kensinger, Elizabeth A.