Lead Exposure in Infancy and Subsequent Growth in Beninese Children.
Lead Exposure in Infancy and Subsequent Growth in Beninese Children.
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DOI：
10.3390/toxics10100595
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发表时间：
2022-10-08
期刊：
影响因子：
4.6
通讯作者：
Bodeau-Livinec F
中科院分区：
文献类型：
--
作者：
Ahmadi S;Botton J;Zoumenou R;Ayotte P;Fievet N;Massougbodji A;Alao MJ;Cot M;Glorennec P;Bodeau-Livinec F
研究表明，产后血铅水平（BLL）升高与儿童生长呈负相关。本研究旨在调查贝宁阿拉达儿童队列中一岁儿童 BLL 与六岁时生长结果 (n = 661) 的关联。研究的生长结果包括年龄别体重 Z 值 (WAZ)、年龄别身高 Z 值 (HAZ)、年龄别体重 Z 值 (BMIZ)、身高别体重 Z 值 (WHZ)、头围 (HC)、生长速度、体重不足、发育迟缓和消瘦。多变量回归模型检查了 BLL 和生长结果之间的关联，并对潜在的混杂因素进行了调整。几何平均 BLL 为 59.3 μg/L，82% 的儿童在 12.8 个月时 BLL >35 μg/L。调整混杂因素后，未发现 BLL 四分位数与 HAZ、WAZ、BMIZ、WHZ、生长速度、消瘦和体重不足之间存在总体关联。然而，与最低四分位的男孩相比，最高四分位的男孩的 HC 低 1.02 厘米（95% CI：[−1.81，-0.24]）。此外，与第一个暴露相比，暴露在最高四分位数的儿童中观察到发育迟缓的几率增加（OR：2.43；95％CI：[1.11-5.33]），这仅在特定性别阶层的女孩中具有统计学意义。研究发现，在资源有限的环境中，血铅与儿童发育迟缓和头围较低的风险增加有关。
Studies suggest that elevated postnatal blood lead levels (BLLs) are negatively associated with child growth. This study aimed to investigate the associations of childhood BLLs at age one year and growth outcomes at age six years (n = 661) in a cohort of children in Allada, Benin. The growth outcomes studied are weight-for-age Z-score (WAZ), height-for-age Z-score (HAZ), BMI-for-age Z-score (BMIZ), weight-for-height Z-score (WHZ), head circumference (HC), growth velocities, underweight, stunting, and wasting. Multivariable regression models examined the associations between BLLs and growth outcomes, with adjustment for potential confounders. The geometric mean BLLs was 59.3 μg/L and 82% of children had BLLs >35 μg/L at the age of 12.8 months. After adjusting for confounding factors, no overall association was found between BLL quartiles and HAZ, WAZ, BMIZ, WHZ, growth velocities, wasting, and underweight. However, boys in the highest quartile had a 1.02 cm lower HC (95% CI: [−1.81, −0.24]) as compared to the lowest quartile. Furthermore, an increased odds of being stunted was observed in children in the highest quartile of exposure compared to the first (OR: 2.43; 95% CI: [1.11–5.33]) which remained statistically significant only among girls in sex-specific strata. Blood lead was found to be associated with an increased risk of childhood stunting and a lower head circumference in a resource-limited setting.
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DOI：
10.1080/09603123.2021.1929871
发表时间：
2022-09
影响因子：
3.2
作者：
Ashley-Martin J;Iannotti L;Lesorogol C;Hilton CE;Olungah CO;Zava T;Needham BL;Cui Y;Brindle E;Straight B
通讯作者：
Straight B
影响因子：
3.7
作者：
Gonete AT;Kassahun B;Mekonnen EG;Takele WW
通讯作者：
Takele WW
DOI：
10.3390/ijerph17228689
发表时间：
2020-11-23
影响因子：
--
作者：
Ahmadi S;Le Bot B;Zoumenou R;Durand S;Fiévet N;Ayotte P;Massougbodji A;Alao MJ;Cot M;Glorennec P;Bodeau-Livinec F
通讯作者：
Bodeau-Livinec F
影响因子：
3.9
作者：
Botton, Jeremie;Scherdel, Pauline;Charles, Marie-Aline
通讯作者：
Charles, Marie-Aline
DOI：
10.1016/j.jtemb.2018.11.005
发表时间：
2019-01-01
影响因子：
3.5
作者：
Jurowski, Kamil;Krosniak, Miroslaw;Piekoszewski, Wojciech
通讯作者：
Piekoszewski, Wojciech