Olfactory Rod Cells: A Rare Cell Type in the Larval Zebrafish Olfactory Epithelium With a Large Actin-Rich Apical Projection.
Olfactory Rod Cells: A Rare Cell Type in the Larval Zebrafish Olfactory Epithelium With a Large Actin-Rich Apical Projection.
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嗅杆细胞:斑马鱼幼鱼嗅上皮中一种罕见的细胞类型,具有大的富含肌动蛋白的顶端突起。
DOI:
10.3389/fphys.2021.626080
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发表时间:
2021
影响因子:
4
通讯作者:
Whitfield TT
中科院分区:
文献类型:
--
作者:
Cheung KY;Jesuthasan SJ;Baxendale S;van Hateren NJ;Marzo M;Hill CJ;Whitfield TT
We report the presence of a rare cell type, the olfactory rod cell, in the developing zebrafish olfactory epithelium. These cells each bear a single actin-rich rod-like apical projection extending 5–10 μm from the epithelial surface. Live imaging with a ubiquitous Lifeact-RFP label indicates that the olfactory rods can oscillate. Olfactory rods arise within a few hours of the olfactory pit opening, increase in numbers and size during larval stages, and can develop in the absence of olfactory cilia. Olfactory rod cells differ in morphology from the known classes of olfactory sensory neuron, but express reporters driven by neuronal promoters. A sub-population of olfactory rod cells expresses a Lifeact-mRFPruby transgene driven by the sox10 promoter. Mosaic expression of this transgene reveals that olfactory rod cells have rounded cell bodies located apically in the olfactory epithelium and have no detectable axon. We offer speculation on the possible function of these cells in the Discussion.
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影响因子:
4.6
作者:
Ahuja G;Bozorg Nia S;Zapilko V;Shiriagin V;Kowatschew D;Oka Y;Korsching SI
通讯作者:
Korsching SI
影响因子:
4.1
作者:
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通讯作者:
Rétaux S
影响因子:
4.6
作者:
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通讯作者:
Wullimann, Mario F.
影响因子:
13.6
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通讯作者:
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影响因子:
56.9
作者:
Behrndt, Martin;Salbreux, Guillaume;Heisenberg, Carl-Philipp
通讯作者:
Heisenberg, Carl-Philipp