The auditory cortex mediates the perceptual effects of acoustic temporal expectation.
The auditory cortex mediates the perceptual effects of acoustic temporal expectation.
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DOI:
10.1038/nn.2688
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发表时间:
2011-02
影响因子:
25
通讯作者:
Zador, Anthony M.
中科院分区:
文献类型:
--
作者:
Jaramillo, Santiago;Zador, Anthony M.
When events occur at predictable instants, anticipation improves performance. Knowledge of event timing modulates motor circuits, improving response speed. By contrast, the neuronal mechanisms underlying changes in sensory perception due to expectation are not well understood. We have developed a novel behavioral paradigm for rats in which we manipulated expectations about sound timing. Valid expectations improved both the speed and the accuracy of subjects’ performance, indicating not only improved motor preparedness but also enhanced perception. Single neuron recordings in primary auditory cortex revealed enhanced representation of sounds during periods of heightened expectation. Furthermore, we found that activity in auditory cortex was causally linked to the performance of the task, and that changes in the neuronal representation of sounds predicted performance on a trial-by-trial basis. Our results indicate that changes in neuronal representation as early as primary sensory cortex mediate the perceptual advantage conferred by temporal expectation.
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影响因子:
25
作者:
Otazu, Gonzalo H.;Tai, Lung-Hao;Yang, Yang;Zador, Anthony M.
通讯作者:
Zador, Anthony M.
影响因子:
--
作者:
SHANNON, CE
通讯作者:
SHANNON, CE
影响因子:
9.8
作者:
Hromádka T;Deweese MR;Zador AM
通讯作者:
Zador AM
影响因子:
2.9
作者:
Correa, A;Lupiáñez, J;Tudela, P
通讯作者:
Tudela, P
影响因子:
56.9
作者:
Kilgard, MP;Merzenich, MM
通讯作者:
Merzenich, MM