Suppression of vascular enhancement artifacts through the use of a multiband, selectively spoiled radiofrequency excitation pulse.

Suppression of vascular enhancement artifacts through the use of a multiband, selectively spoiled radiofrequency excitation pulse.
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DOI:
10.1002/jmri.22523
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发表时间:
2011-05
影响因子:
4.4
通讯作者:
Bankson, James A.
Bankson, James A.
中科院分区:
医学2区
文献类型:
--
作者:
Ragan, Dustin K.;Bankson, James A.

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旨在测试多波段RF脉冲在不影响时间分辨率或空间覆盖范围的情况下减少稳态成像的血流增强伪影的能力。选择性破坏复合射频脉冲,提供同时激励和流动准备的设计和测试,通过模拟,幻影,并在不同条件下的流动在体内测量。抑制流动增强被发现取决于流速和空间范围的破坏区域。通过确定给定实验几何形状的必要脉冲特性,降低了血流增强,并显著增加了对T1降低造影剂的敏感性。这些脉冲提供了抑制流动增强的有效手段,而不牺牲时间分辨率或空间覆盖范围。
To test the ability of a multi-band RF pulse to reduce flow enhancement artifacts for steady state imaging without compromising temporal resolution or spatial coverage. Selectively spoiled composite RF pulses that provide simultaneous excitation and flow preparation were designed and tested via simulation, phantom, and in vivo measurements under varying conditions of flow. Suppression of flow enhancement was found to depend on flow velocity and spatial extent of spoiled regions. By determining necessary pulse characteristics for a given experimental geometry, flow enhancement was reduced and sensitivity to T1-reducing contrast agent was dramatically increased. These pulses provide an effective means of suppressing flow enhancement without sacrificing temporal resolution or spatial coverage.
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