The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.
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DOI：
10.1038/sj.bjc.6602550
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发表时间：
2005-05-09
影响因子：
8.8
通讯作者：
Pharmacodynamic/Pharmacokinetic Technologies Advisory Committee, Drug Development Office, Cancer Research UK
中科院分区：
文献类型：
--
作者：
Leach MO;Brindle KM;Evelhoch JL;Griffiths JR;Horsman MR;Jackson A;Jayson GC;Judson IR;Knopp MV;Maxwell RJ;McIntyre D;Padhani AR;Price P;Rathbone R;Rustin GJ;Tofts PS;Tozer GM;Vennart W;Waterton JC;Williams SR;Workman P;Pharmacodynamic/Pharmacokinetic Technologies Advisory Committee, Drug Development Office, Cancer Research UK
血管和血管生成过程为新型癌症治疗提供了重要靶点。动态对比增强磁共振成像越来越多地用于在早期临床试验中无创监测这些疗法的作用。本出版物报告了一次研讨会的成果，该研讨会考虑了磁共振研究的方法和设计，并就如何最好地使用这一新工具提出了建议。
Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.
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影响因子：
2.9
作者：
Hayes, C;Padhani, AR;Leach, MO
通讯作者：
Leach, MO
影响因子：
2.6
作者：
Brookes, JA;Redpath, TW;Murray, AD
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Murray, AD
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2.2
作者：
Choyke, PL;Knopp, MV;Libutti, SK
通讯作者：
Libutti, SK
影响因子：
9.6
作者：
George, ML;Dzik-Jurasz, ASK;Swift, RI
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Swift, RI
影响因子：
3.3
作者：
Brasch, R;Turetschek, K
通讯作者：
Turetschek, K