COVID-19 and NSTEMI Outcomes among Hospitalized Patients in the United States and Racial Disparities in Mortality: Insight from National Inpatient Sample Database.
COVID-19 and NSTEMI Outcomes among Hospitalized Patients in the United States and Racial Disparities in Mortality: Insight from National Inpatient Sample Database.
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DOI：
10.3390/vaccines10122024
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发表时间：
2022-11-26
期刊：
影响因子：
7.8
通讯作者：
Sheikh AB
中科院分区：
文献类型：
--
作者：
Majeed H;Gangu K;Sagheer S;Garg I;Khan U;Shuja H;Bobba A;Chourasia P;Shekhar R;Avula SR;Sheikh AB
COVID-19大流行影响了向非ST段抬高型心肌梗死（NSTEMI）患者提供的医疗保健服务。我们回顾性研究的目的是确定COVID-19对住院NSTEMI结局的影响，并调查心脏护理的变化是否有助于观察到的结局。经过多变量调整后，我们发现患有COVID-19的NSTEMI患者的住院死亡率较高（37.3% vs. 7.3%，校正比值比：4.96，95% CI：4.6-5.4，p < 0.001），住院时间延长（9.9天vs. 5.4天，调整后的LOS：延长3.6天，p < 0.001），住院费用较高（150，000美元vs. 110，000美元，通货膨胀调整后的住院费用：高36，000美元，p < 0.001）与非COVID-19的NSTEMI患者相比，尽管既存心脏合并症的负担较低。患有COVID-19的NSTEMI患者也接受了微创心脏手术（冠状动脉造影：8.7% vs. 50.3%，p < 0.001; PCI：4.8% vs. 29%，p < 0.001; CABG：0.7% vs. 6.2%，p < 0.001）。在我们的研究中，我们观察到死亡率和住院并发症增加是COVID-19感染和心肌炎症的综合影响，这是细胞因子风暴、促血栓状态、氧气供需失衡和医疗服务变化造成的。2020年1月至12月。
The COVID-19 pandemic has impacted healthcare delivery to patients with non-ST-segment elevation myocardial infraction (NSTEMI). The aim of our retrospective study is to determine the effect of COVID-19 on inpatient NSTEMI outcomes and to investigate whether changes in cardiac care contributed to the observed outcomes. After multivariate adjustment, we found that NSTEMI patients with COVID-19 had a higher rate of inpatient mortality (37.3% vs. 7.3%, adjusted odds ratio: 4.96, 95% CI: 4.6–5.4, p < 0.001), increased length of stay (9.9 days vs. 5.4 days, adjusted LOS: 3.6 days longer, p < 0.001), and a higher cost of hospitalization (150,000 USD vs. 110,000 USD, inflation-adjusted cost of hospitalization: 36,000 USD higher, p < 0.001) in comparison to NSTEMI patients without COVID-19, despite a lower burden of pre-existing cardiac comorbidity. NSTEMI patients with COVID-19 also received less invasive cardiac procedures (coronary angiography: 8.7% vs. 50.3%, p < 0.001; PCI: 4.8% vs. 29%, p < 0.001; and CABG: 0.7% vs. 6.2%, p < 0.001). In our study, we observed increased mortality and in-hospital complications to be a combined effect of COVID-19 infection and myocardial inflammation as a result of cytokine storm, prothrombic state, oxygen supply/demand imbalance and alterations in healthcare delivery from January to December 2020.
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影响因子：
2.9
作者：
Pourasghari, Hamid;Tavolinejad, Hamed;Soleimanpour, Samira;Abdi, Zhaleh;Arabloo, Jalal;Bragazzi, Nicola Luigi;Behzadifar, Masoud;Rashedi, Sina;Omidi, Negar;Ayoubian, Ali;Tajdini, Masih;Ghorashi, Seyyed Mojtaba;Azari, Samad
通讯作者：
Azari, Samad
影响因子：
13.8
作者：
Muñoz-Price LS;Nattinger AB;Rivera F;Hanson R;Gmehlin CG;Perez A;Singh S;Buchan BW;Ledeboer NA;Pezzin LE
通讯作者：
Pezzin LE
影响因子：
24
作者：
De Luca G;Verdoia M;Cercek M;Jensen LO;Vavlukis M;Calmac L;Johnson T;Ferrer GR;Ganyukov V;Wojakowski W;Kinnaird T;van Birgelen C;Cottin Y;IJsselmuiden A;Tuccillo B;Versaci F;Royaards KJ;Berg JT;Laine M;Dirksen M;Siviglia M;Casella G;Kala P;Díez Gil JL;Banning A;Becerra V;De Simone C;Santucci A;Carrillo X;Scoccia A;Amoroso G;Lux A;Kovarnik T;Davlouros P;Mehilli J;Gabrielli G;Rios XF;Bakraceski N;Levesque S;Cirrincione G;Guiducci V;Kidawa M;Spedicato L;Marinucci L;Ludman P;Zilio F;Galasso G;Fabris E;Menichelli M;Garcia-Touchard A;Manzo S;Caiazzo G;Moreu J;Forés JS;Donazzan L;Vignali L;Teles R;Benit E;Agostoni P;Bosa Ojeda F;Lehtola H;Camacho-Freiere S;Kraaijeveld A;Antti Y;Boccalatte M;Deharo P;Martínez-Luengas IL;Scheller B;Alexopoulos D;Moreno R;Kedhi E;Uccello G;Faurie B;Gutierrez Barrios A;Di Uccio FS;Wilbert B;Smits P;Cortese G;Parodi G;Dudek D
通讯作者：
Dudek D
DOI：
10.1161/circinterventions.120.009654
发表时间：
2020-11-01
影响因子：
5.6
作者：
Kwok, Chun Shing;Gale, Chris P.;Mamas, Mamas A.
通讯作者：
Mamas, Mamas A.
影响因子：
5.4
作者：
Chi, Gloria C.;Kanter, Michael H.;Reynolds, Kristi
通讯作者：
Reynolds, Kristi