Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set.
Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set.
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DOI:
10.1038/s41592-021-01183-7
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发表时间:
2021-07
期刊:
影响因子:
48
通讯作者:
Funke J
中科院分区:
文献类型:
--
作者:
Buhmann J;Sheridan A;Malin-Mayor C;Schlegel P;Gerhard S;Kazimiers T;Krause R;Nguyen TM;Heinrich L;Lee WA;Wilson R;Saalfeld S;Jefferis GSXE;Bock DD;Turaga SC;Cook M;Funke J
We developed an automatic method for synaptic partner identification in insect brains and use it to predict synaptic partners in a whole-brain electron microscopy dataset of the fruit fly. Those predictions can be used to infer a connectivity graph with high accuracy, thus allowing fast identification of neural pathways. To facilitate circuit reconstruction using our results, we developed CircuitMap, a user interface add-on for the circuit annotation tool Catmaid.
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