The Sec-dependent pathway.
The Sec-dependent pathway.
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DOI:
10.1016/j.resmic.2013.03.007
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发表时间:
2013-07
影响因子:
2.6
通讯作者:
Beckwith, Jon
中科院分区:
文献类型:
--
作者:
Beckwith, Jon
The Sec pathway for export of proteins across the cytoplasmic membrane to the bacterial periplasm and outer membrane was the first secretion pathway to be discovered in bacteria. A combination of bacterial genetics, development of an in vitro membrane vesicle system and the concurrent elaboration of the signal hypothesis from studies on eukaryotes led to the identification and characterization of two pathways leading to protein export through the SecYEG cytoplasmic membrane translocon. The Sec pathway is also required for assembly of proteins into the cytoplasmic membrane. Since the membrane translocon for Sec pathways is conserved across the three domains of life, the history of research progress in eukaryotes and bacteria was facilitated by the close interaction between those studying both classes of organisms.
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影响因子:
1.6
作者:
Fang, Jun;Wei, Yinan
通讯作者:
Wei, Yinan
影响因子:
3.2
作者:
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影响因子:
11.4
作者:
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通讯作者:
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DOI:
10.1073/pnas.74.3.1004
发表时间:
1977-01-01
影响因子:
11.1
作者:
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通讯作者:
INOUYE, M
影响因子:
64.8
作者:
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通讯作者:
BECKWITH, J