Acetochlor affects zebrafish ovarian development by producing estrogen effects and inducing oxidative stress
Acetochlor affects zebrafish ovarian development by producing estrogen effects and inducing oxidative stress
复制标题
乙草胺通过产生雌激素作用和诱导氧化应激来影响斑马鱼卵巢发育
DOI：
10.1007/s11356-020-09050-2
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发表时间：
2020-05
影响因子：
5.8
通讯作者：
Wenzhi Wei
中科院分区：
文献类型：
--
作者：
Yingying Zhang;Wen Xue;Runze Long;Hui Yang;Wenzhi Wei
Acetochlor is one of the most widely used pesticides worldwide and widely distributed in the water environment. However, studies on the reproductive influence of acetochlor are still limited. To investigate the impact and potential mechanism of acetochlor on fish ovarian development, zebrafish were utilized as experiment models. The ovarian histology, ovarian development-related genes, and plasma oxidative stress-related indexes were investigated following acetochlor (at nominal concentration 1, 10, and 100 μg/L) exposure for 7 and 21 days. Results showed that low-dose acetochlor had estrogen effect and induced zebrafish estradiol (E2) and ovarian vitellogenin (Vtg) synthesis and promoted ovarian development, while long-term exposure to higher doses of acetochlor reduced the ability of ovarian resistance to oxidative stress and destroyed the development of the ovary. Moreover, bone morphogenetic protein 15 (bmp15) and growth differentiation factor 9 (gdf9) were also involved in the influence of acetochlor on the ovarian development of zebrafish.
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DOI：
10.1186/1477-7827-10-49
发表时间：
2012-06-29
期刊：
Reproductive biology and endocrinology : RB&E
影响因子：
--
作者：
Agarwal A;Aponte-Mellado A;Premkumar BJ;Shaman A;Gupta S
通讯作者：
Gupta S
影响因子：
2.1
作者：
Xianping Song;Feng Zhang;Dongya Chen;Qian Bian;Hengdong Zhang;Xin Liu;B. Zhu
通讯作者：
Xianping Song;Feng Zhang;Dongya Chen;Qian Bian;Hengdong Zhang;Xin Liu;B. Zhu
影响因子：
2.7
作者：
Paul D. Jones;W. Coen;L. Tremblay;J. Giesy
通讯作者：
Paul D. Jones;W. Coen;L. Tremblay;J. Giesy
DOI：
--
发表时间：
2014-05
期刊：
Huan jing ke xue= Huanjing kexue
影响因子：
--
作者：
Zhi-yong Yu;Fen Jin;Hongyan Li;W. An;Min Yang
通讯作者：
Zhi-yong Yu;Fen Jin;Hongyan Li;W. An;Min Yang
影响因子：
6.9
作者：
Xiaoyin Sun;Qixing Zhou;Wenjie Ren;Xuhui Li;L. Ren
通讯作者：
Xiaoyin Sun;Qixing Zhou;Wenjie Ren;Xuhui Li;L. Ren