Childhood Trajectories of Hyperactivity/Inattention Symptoms and Diurnal Cortisol in Middle Adolescence: Results from a UK Birth Cohort.
Childhood Trajectories of Hyperactivity/Inattention Symptoms and Diurnal Cortisol in Middle Adolescence: Results from a UK Birth Cohort.
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DOI:
10.1177/10870547211036755
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发表时间:
2022-04
影响因子:
3
通讯作者:
Francesconi M
中科院分区:
文献类型:
--
作者:
Ji D;Flouri E;Papachristou E;Francesconi M
Children with attention-deficit/hyperactivity disorder (ADHD) show hypoactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Whether the association between hyperactivity/inattention symptoms with HPA axis dysfunction holds in the general child population too is not clear. We assessed associations between longitudinal trajectories of hyperactivity/inattention symptoms during ages 4 to 13 years and basal cortisol profiles at age 15 in a British general population cohort. Adolescents with persistently high levels of hyperactivity/inattention symptoms since childhood showed lower total morning cortisol and a smaller diurnal decline, even after adjusting for confounders. No associations were found between any of the symptom trajectories and cortisol awakening response, diurnal slope or daily output of cortisol. This study provides evidence for hypocortisolism among adolescents with chronic hyperactivity/inattention symptoms in the general population.
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影响因子:
6.6
作者:
Flouri, Eirini;Francesconi, Marta;Lewis, Glyn
通讯作者:
Lewis, Glyn
DOI:
10.1192/bjp.bp.113.126250
发表时间:
2014-02
期刊:
The British journal of psychiatry : the journal of mental science
影响因子:
--
作者:
Carnegie R;Araya R;Ben-Shlomo Y;Glover V;O'Connor TG;O'Donnell KJ;Pearson R;Lewis G
通讯作者:
Lewis G
影响因子:
3.7
作者:
Adam EK;Quinn ME;Tavernier R;McQuillan MT;Dahlke KA;Gilbert KE
通讯作者:
Gilbert KE
影响因子:
3.5
作者:
Fortier, Marie-Eve;Sengupta, Sarojini M.;Joober, Ridha
通讯作者:
Joober, Ridha
DOI:
10.1097/dbp.0000000000000626
发表时间:
2019-02-01
影响因子:
2.4
作者:
Bax, Ami C.;Bard, David E.;Wolraich, Mark L.
通讯作者:
Wolraich, Mark L.