Spinal cord MRI at 7T.

Spinal cord MRI at 7T.
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DOI:
10.1016/j.neuroimage.2017.07.003
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发表时间:
2018-03
期刊:
影响因子:
5.7
通讯作者:
Smith SA
Smith SA
中科院分区:
医学1区
文献类型:
--
作者:
Barry RL;Vannesjo SJ;By S;Gore JC;Smith SA

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7特斯拉的人类脊髓磁共振成像(MRI)已经在世界范围内的一些研究地点得到了证实,脊髓仍然是高场强和高分辨率可能产生高影响的领域之一。脊髓的小直径(约1厘米)需要高空间分辨率,以尽量减少灰质和白质之间的部分体积效应,因此脊髓的MRI可以极大地受益于增加的信噪比和超高场(UHF)对比度。在此,我们回顾了超高频脊髓成像的现状。成功进行超高频脊髓MRI的技术挑战包括射频(B1)不均匀性,普遍缺乏优化的射频线圈,放大的生理噪声,以及缺乏沿脊髓进行稳健的B0振荡以减轻图像失真和信号损失的方法。解决这些挑战的许多解决方案已经并且正在继续探索,包括信号激励和采集的新方法,动态摆振和专用垫片线圈,以及增加覆盖范围或最佳切片角度的采集。
Magnetic resonance imaging (MRI) of the human spinal cord at 7 Tesla has been demonstrated by a handful of research sites worldwide, and the spinal cord remains one of the areas in which higher fields and resolution could have high impact. The small diameter of the cord (~1 cm) necessitates high spatial resolution to minimize partial volume effects between gray and white matter, and so MRI of the cord can greatly benefit from increased signal-to-noise ratio and contrasts at ultra-high field (UHF). Herein we review the current state of UHF spinal cord imaging. Technical challenges to successful UHF spinal cord MRI include radiofrequency (B1) nonuniformities and a general lack of optimized radiofrequency coils, amplified physiological noise, and an absence of methods for robust B0 shimming along the cord to mitigate image distortions and signal losses. Numerous solutions to address these challenges have been and are continuing to be explored, and include novel approaches for signal excitation and acquisition, dynamic shimming and specialized shim coils, and acquisitions with increased coverage or optimal slice angulations.
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