Establishment of quantitative indicators for an efficient treatment on masticatory muscle pain.
Establishment of quantitative indicators for an efficient treatment on masticatory muscle pain.
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DOI：
10.1002/cre2.705
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发表时间：
2023-02
影响因子：
1.8
通讯作者：
Cheon, Kyounga
中科院分区：
文献类型：
--
作者：
Lee, Sunhee;Ju, Hye-Min;Ho, Donald;Song, Byong-Sop;Jeong, Sung-Hee;Ahn, Yong-Woo;Ok, Soo-Min;Cheon, Kyounga
关键词：
虽然有几项研究调查了咀嚼肌疼痛（MMP）的有效治疗方法，但关于这些治疗方法的有效性尚未得出统一的结论。本研究的目的是确定预测MMP治疗结果的定量指标。根据颞下颌关节紊乱病的诊断标准，共招募了20-70岁的患者，并根据MMP的存在分为MMP组（n = 24）和对照组（n = 36）。在治疗前，MMP组采用主观疼痛水平、疼痛持续时间、慢性疼痛分级量表（GCPS）和感知压力量表（PSS）等定量指标进行评估。分析了唾液α-淀粉酶（sAA）和白细胞介素-6（IL-6）水平。测量咀嚼肌触诊评分和张口度。在治疗后，检查主观疼痛水平、张口度和治疗/用药持续时间。对照组测定PSS和sAA水平。MMP组sAA水平显著高于对照组（p <0.05）。咬肌触诊评分（MPS）与IL-6水平呈正相关（ρ = 0.503，p <0.05），与非甾体抗炎药（NSAID）治疗时间呈负相关（ρ =-0.462，p <0.05）。颞肌触诊评分（TPS）与疼痛持续时间和GCPS分级呈正相关（分别为ρ = 0.483，p <0.05和ρ = 0.445，p <0.05）。NSAID治疗在MPS和IL-6水平高的MMP组中有效，但在TPS、疼痛持续时间和GCPS等级高的MMP组中无效。
Although several studies have investigated effective treatments for masticatory muscle pain (MMP), no unified conclusion has been drawn regarding the effectiveness of these treatments. This study aimed to define quantitative indicators for predicting the outcome of MMP treatment. In total, patients aged 20–70 years were recruited and divided into the MMP (n = 24) and control (n = 36) groups, based on the presence of MMP according to the Diagnostic Criteria for Temporomandibular Disorders. At pretreatment, the MMP group was assessed using quantitative indicators such as subjective pain levels, pain duration, graded chronic pain scale (GCPS), and perceived stress scale (PSS). Salivary alpha‐amylase (sAA) and interleukin‐6 (IL‐6) levels were analyzed. The masticatory muscle palpation score and the range of mouth opening were measured. At posttreatment, subjective pain levels, mouth opening, and treatment/medication duration were examined. The PSS and sAA levels were assessed in the control group. sAA levels in the MMP group were significantly higher than those in the control group (p < .05). The masseter muscle palpation score (MPS) showed a positive correlation with IL‐6 levels (ρ = 0.503, p < .05) and a negative correlation with nonsteroidal anti‐inflammatory drug (NSAID) treatment period (ρ = −0.462, p < .05). The temporalis muscle palpation score (TPS) was positively correlated with pain duration and GCPS grade (ρ = 0.483, p < .05, and ρ = 0.445, p < .05, respectively). Treatment with NSAIDs was effective in the MMP group with high MPS and IL‐6 levels, but not in the MMP group with high TPS, pain duration, and GCPS grade.
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影响因子：
2.5
作者：
Kobayashi, Fernanda Yukie;Gaviao, Maria Beatriz Duarte;Castelo, Paula Midori
通讯作者：
Castelo, Paula Midori
影响因子：
3.7
作者：
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Dima-Cozma LC
DOI：
10.1177/2470547017704763
发表时间：
2017-03
期刊：
Chronic stress (Thousand Oaks, Calif.)
影响因子：
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作者：
Abdallah CG;Geha P
通讯作者：
Geha P
影响因子：
3.7
作者：
Nater, Urs M.;Rohleder, Nicolas;Kirschbaum, Clemens
通讯作者：
Kirschbaum, Clemens
DOI：
10.1016/j.rehab.2019.06.019
发表时间：
2020-05-01
影响因子：
4.6
作者：
Assadourian, Marina;Bailly, Florian;Gossec, Laure
通讯作者：
Gossec, Laure