Repeated horizontal transfers of four DNA transposons in invertebrates and bats.
Repeated horizontal transfers of four DNA transposons in invertebrates and bats.
复制标题
无脊椎动物和蝙蝠中四个 DNA 转座子的重复水平转移
DOI：
10.1186/s13100-014-0033-1
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发表时间：
2015
期刊：
影响因子：
4.9
通讯作者：
Zhang Z
中科院分区：
文献类型：
--
作者：
Tang Z;Zhang HH;Huang K;Zhang XG;Han MJ;Zhang Z
转座因子（te）向新基因组的水平转移（HT）被认为是推动基因组变异和生物创新的重要力量。然而，先前描述的大多数DNA转座子的HT发生在密切相关的物种或昆虫之间。结果本研究对首次测序的扭曲翼寄生虫Mengenilla moldrzyki中的4个DNA转座子进行了详细分析。通过同源性策略，这些转座子也在其他昆虫、淡水涡虫、水生动物和蝙蝠中被鉴定出来。这些转座子的系统发育分布是不连续的，尽管它们的宿主在3亿多年前（Mya）就开始分化，但它们在整个长度上显示出极高的序列一致性（>87%）。此外，系统发育和转座子与同源基因身份的比较表明，这些转座子是通过独立的HTs转移到宿主体内的。本文提供了迄今为止在植物中广泛研究的仙人掌转座子的HT的第一个文献例子。我们的研究结果表明，蝙蝠通过HT不断获得新的DNA元素。这意味着捕食大量昆虫可能会增加蝙蝠对高温辐射的暴露。此外，寄主与寄生虫的相互作用可能促进遗传物质的交换。
BackgroundHorizontal transfer (HT) of transposable elements (TEs) into a new genome is considered as an important force to drive genome variation and biological innovation. However, most of the HT of DNA transposons previously described occurred between closely related species or insects.ResultsIn this study, we carried out a detailed analysis of four DNA transposons, which were found in the first sequenced twisted-wing parasite,Mengenilla moldrzyki. Through the homology-based strategy, these transposons were also identified in other insects, freshwater planarian, hydrozoans, and bats. The phylogenetic distribution of these transposons was discontinuous, and they showed extremely high sequence identities (>87%) over their entire length in spite of their hosts diverging more than 300 million years ago (Mya). Additionally, phylogenies and comparisons of transposons versus orthologous gene identities demonstrated that these transposons have transferred into their hosts by independent HTs.ConclusionsHere, we provided the first documented example of HT ofCACTAtransposons, which have been so far extensively studied in plants. Our results demonstrated that bats had continuously acquired new DNA elements via HT. This implies that predation on a large quantity of insects might increase bat exposure to HT. In addition, parasite-host interaction might facilitate exchanging of their genetic materials.
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影响因子：
64.8
作者：
Dasmahapatra, Kanchon K.;Walters, James R.;Briscoe, Adriana D.;Davey, John W.;Whibley, Annabel;Nadeau, Nicola J.;Zimin, Aleksey V.;Hughes, Daniel S. T.;Ferguson, Laura C.;Martin, Simon H.;Salazar, Camilo;Lewis, James J.;Adler, Sebastian;Ahn, Seung-Joon;Baker, Dean A.;Baxter, Simon W.;Chamberlain, Nicola L.;Chauhan, Ritika;Counterman, Brian A.;Dalmay, Tamas;Gilbert, Lawrence E.;Gordon, Karl;Heckel, David G.;Hines, Heather M.;Hoff, Katharina J.;Holland, Peter W. H.;Jacquin-Joly, Emmanuelle;Jiggins, Francis M.;Jones, Robert T.;Kapan, Durrell D.;Kersey, Paul;Lamas, Gerardo;Lawson, Daniel;Mapleson, Daniel;Maroja, Luana S.;Martin, Arnaud;Moxon, Simon;Palmer, William J.;Papa, Riccardo;Papanicolaou, Alexie;Pauchet, Yannick;Ray, David A.;Rosser, Neil;Salzberg, Steven L.;Supple, Megan A.;Surridge, Alison;Tenger-Trolander, Ayse;Vogel, Heiko;Wilkinson, Paul A.;Wilson, Derek;Yorke, James A.;Yuan, Furong;Balmuth, Alexi L.;Eland, Cathlene;Gharbi, Karim;Thomson, Marian;Gibbs, Richard A.;Han, Yi;Jayaseelan, Joy C.;Kovar, Christie;Mathew, Tittu;Muzny, Donna M.;Ongeri, Fiona;Pu, Ling-Ling;Qu, Jiaxin;Thornton, Rebecca L.;Worley, Kim C.;Wu, Yuan-Qing;Linares, Mauricio;Blaxter, Mark L.;Ffrench-Constant, Richard H.;Joron, Mathieu;Kronforst, Marcus R.;Mullen, Sean P.;Reed, Robert D.;Scherer, Steven E.;Richards, Stephen;Mallet, James;McMillan, W. Owen;Jiggins, Chris D.
通讯作者：
Jiggins, Chris D.
影响因子：
1.7
作者：
Lack, Justin B.;Van Den Bussche, Ronald A.
通讯作者：
Van Den Bussche, Ronald A.
影响因子：
4.9
作者：
Lavoie CA;Platt RN 2nd;Novick PA;Counterman BA;Ray DA
通讯作者：
Ray DA
影响因子：
3.4
作者：
DeMarco R;Venancio TM;Verjovski-Almeida S
通讯作者：
Verjovski-Almeida S
影响因子：
14.9
作者：
Duan J;Li R;Cheng D;Fan W;Zha X;Cheng T;Wu Y;Wang J;Mita K;Xiang Z;Xia Q
通讯作者：
Xia Q