MUGEN mouse database; animal models of human immunological diseases.

MUGEN mouse database; animal models of human immunological diseases.
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Mugen鼠标数据库;人类免疫疾病的动物模型。

DOI:
10.1093/nar/gkm838
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Kollias, G.
Kollias, G.
中科院分区:
生物学2区
文献类型:
--
作者:
Aidinis, V.;Chandras, C.;Manoloukos, M.;Thanassopoulou, A.;Kranidioti, K.;Armaka, M.;Douni, E.;Kontoyiannis, D. L.;Zouberakis, M.;Kollias, G.

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Mugen小鼠数据库(MMdb)(www.mugen-noe.org/database/)是一个关于小鼠免疫过程和免疫疾病模型的数据库。其目的是分享和宣传参与机构提供的关于老鼠品系特征和可获得性的信息。MMDB对模型的基本分类是基于三个主要的研究应用类别:人类疾病模型、免疫过程模型和转基因工具。突变株的数据包括有关致病基因(S)、突变等位基因(S)和遗传背景(脱氧核糖核酸来源、靶标基因、寄主和回交菌株背景)的详细信息。每个基因/转基因索引还包括ID和指向EnSembl、ArrayExpress、EURExpress和NCBI的Entrez基因数据库的直接链接。表型描述是标准化和层次化结构的,基于MGI的哺乳动物表型本体论术语。明确说明可获得性(例如,活体小鼠、冷冻胚胎、精子和胚胎干细胞),以及处理和基因分型细节(以文件或超链接的形式)和所有相关联系信息(如有,包括Emma和JAX/IMSR超链接)。MMdb的设计提供了一个用户友好的查询界面,并提供了对突变菌株和基因列表的即时访问。数据库访问是免费的,数据查询也没有注册要求。
The MUGEN mouse database (MMdb) (www.mugen-noe.org/database/) is a database of murine models of immune processes and immunological diseases. Its aim is to share and publicize information on mouse strain characteristics and availability from participating institutions. MMdb's basic classification of models is based on three major research application categories: Models of Human Disease, Models of Immune Processes and Transgenic Tools. Data on mutant strains includes detailed information on affected gene(s), mutant allele(s) and genetic background (DNA origin, gene targeted, host and backcross strain background). Each gene/transgene index also includes IDs and direct links to Ensembl, ArrayExpress, EURExpress and NCBI's Entrez Gene database. Phenotypic description is standardized and hierarchically structured, based on MGI's mammalian phenotypic ontology terms. Availability (e.g. live mice, cryopreserved embryos, sperm and ES cells) is clearly indicated, along with handling and genotyping details (in the form of documents or hyperlinks) and all relevant contact information (including EMMA and Jax/IMSR hyperlinks where available). MMdb's design offers a user-friendly query interface and provides instant access to the list of mutant strains and genes. Database access is free of charge and there are no registration requirements for data querying.
DOI: 10.1186/gb-2004-6-1-r7
发表时间: 2005
期刊: Genome biology
影响因子: 12.3
作者:
Smith CL;Goldsmith CA;Eppig JT
通讯作者: Eppig JT
DOI: 10.1093/nar/gkl1031
发表时间: 2007-01-01
影响因子: 14.9
作者:
Wheeler, David L.;Barrett, Tanya;Yaschenko, Eugene
通讯作者: Yaschenko, Eugene
DOI: 10.1093/nar/gkl993
发表时间: 2007-01
影响因子: 14.9
作者:
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通讯作者: Tatusova, Tatiana
DOI: 10.1186/gb-2004-6-1-r8
发表时间: 2005
期刊: Genome biology
影响因子: 12.3
作者:
Gkoutos GV;Green EC;Mallon AM;Hancock JM;Davidson D
通讯作者: Davidson D
DOI: 10.1006/geno.2001.6513
发表时间: 2001-05-15
期刊: GENOMICS
影响因子: 4.4
作者:
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通讯作者: Blake, JA