The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information.

The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information.
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DOI:
10.1186/gb-2004-6-1-r7
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发表时间:
2005
期刊:
影响因子:
12.3
通讯作者:
Eppig JT
Eppig JT
中科院分区:
生物学1区
文献类型:
--
作者:
Smith CL;Goldsmith CA;Eppig JT

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哺乳动物表型(MP)本体论可以在突变,定量性状基因座和菌株的背景下对哺乳动物表型进行强有力的注释,这些菌株被用作人类生物学和疾病的模型。 哺乳动物表型(MP)本体论可以在突变,定量性状基因座和菌株的背景下对哺乳动物表型进行强有力的注释,这些菌株被用作人类生物学和疾病的模型。 MP本体学支持表型知识的不同水平和丰富性以及对个别基因型的灵活注释。它通过研究小组,诱变联盟和生物领域专家的协作输入继续动态发展。 MP本体论当前由小鼠基因组数据库和大鼠基因组数据库使用来表示表型数据。
The Mammalian Phenotype (MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and disease. The Mammalian Phenotype (MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and disease. The MP Ontology supports different levels and richness of phenotypic knowledge and flexible annotations to individual genotypes. It continues to develop dynamically via collaborative input from research groups, mutagenesis consortia, and biological domain experts. The MP Ontology is currently used by the Mouse Genome Database and Rat Genome Database to represent phenotypic data.
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