Meiosis in allopolyploid Arabidopsis suecica.
Meiosis in allopolyploid Arabidopsis suecica.
复制标题
异源多倍体拟南芥的减数分裂。
DOI：
10.1111/tpj.15879
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发表时间：
2022-08
期刊：
影响因子：
7.2
通讯作者：
Lloyd, Andrew
中科院分区：
文献类型：
--
作者：
Nibau, Candida;Gonzalo, Adrian;Evans, Aled;Sweet-Jones, William;Phillips, Dylan;Lloyd, Andrew
关键词：
多倍体是真核生物进化的主要动力，但对减数分裂染色体分离提出了挑战。因此，第一代多倍体通常比已建立的野生多倍体群体遭受更多的减数分裂错误和较低的生育力。已建立的多倍体如何适应其减数分裂行为，以确保基因组的稳定性和准确的染色体分离仍然是一个积极的研究问题。本文报道了异源多倍体模式植物拟南芥（Arabidopsis suecica，2n = 4x = 26）减数分裂的细胞学特征。A. suecica是二倍体样的，具有正常的突触进展，并且没有突触伴侣交换的证据。在低频率下观察到一些异常，包括中期I的单价体、后期桥和中期II的非整倍体;然而，我们没有看到非同源染色体之间发生交叉形成的证据。A中的交叉数。Suecica与其二倍体亲本拟南芥（Arabidopsis thaliana）（2n = 2x = 10）和拟南芥（Arabidopsis arenosa）（2n = 2x = 16）报道的组合数目相似，平均每个染色体对约1.75次交换。这与自然进化的同源四倍体A. arenosa，其中通过将交叉限制在每对染色体约1个来实现精确的染色体分离。虽然同源四倍体供体被假设为贡献了A。arenosa亚基因组到A. suecica、刺萼草A. suecica具有二倍体A. arenosa变异的关键减数分裂基因。这些多方面的证据表明，在最近进化的异源多倍体A。Suecica基本上是二倍体样的，减数分裂适应遵循与同源四倍体A所描述的非常不同的轨迹。arenosa。在这篇手稿中，我们描述了异源多倍体模式物种拟南芥的减数分裂，表明减数分裂和控制它的基因基本上是二倍体样的。异源多倍体A.因此，suecica遵循与先前描述的同源四倍体A非常不同的途径。arenosa。
Polyploidy is a major force shaping eukaryote evolution but poses challenges for meiotic chromosome segregation. As a result, first‐generation polyploids often suffer from more meiotic errors and lower fertility than established wild polyploid populations. How established polyploids adapt their meiotic behaviour to ensure genome stability and accurate chromosome segregation remains an active research question. We present here a cytological description of meiosis in the model allopolyploid species Arabidopsis suecica (2n = 4x = 26). In large part meiosis in A. suecica is diploid‐like, with normal synaptic progression and no evidence of synaptic partner exchanges. Some abnormalities were seen at low frequency, including univalents at metaphase I, anaphase bridges and aneuploidy at metaphase II; however, we saw no evidence of crossover formation occurring between non‐homologous chromosomes. The crossover number in A. suecica is similar to the combined number reported from its diploid parents Arabidopsis thaliana (2n = 2x = 10) and Arabidopsis arenosa (2n = 2x = 16), with an average of approximately 1.75 crossovers per chromosome pair. This contrasts with naturally evolved autotetraploid A. arenosa, where accurate chromosome segregation is achieved by restricting crossovers to approximately 1 per chromosome pair. Although an autotetraploid donor is hypothesized to have contributed the A. arenosa subgenome to A. suecica, A. suecica harbours diploid A. arenosa variants of key meiotic genes. These multiple lines of evidence suggest that meiosis in the recently evolved allopolyploid A. suecica is essentially diploid like, with meiotic adaptation following a very different trajectory to that described for autotetraploid A. arenosa. In this manuscript we describe meiosis in the allopolyploid model species Arabidopsis suecica, showing that meiosis, and the genes controlling it, are essentially diploid‐like. Meiotic adaptation in allopolyploid A. suecica therefore follows a very different route to that previously described for autotetraploid A. arenosa.
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影响因子：
3.1
作者：
Kawabe, A;Nasuda, S
通讯作者：
Nasuda, S
影响因子：
16.8
作者：
Burns R;Mandáková T;Gunis J;Soto-Jiménez LM;Liu C;Lysak MA;Novikova PY;Nordborg M
通讯作者：
Nordborg M
DOI：
10.15252/embj.2020104858
发表时间：
2020-11-02
期刊：
The EMBO journal
影响因子：
--
作者：
Blackwell AR;Dluzewska J;Szymanska-Lejman M;Desjardins S;Tock AJ;Kbiri N;Lambing C;Lawrence EJ;Bieluszewski T;Rowan B;Higgins JD;Ziolkowski PA;Henderson IR
通讯作者：
Henderson IR
影响因子：
5.6
作者：
Higgins JD;Wright KM;Bomblies K;Franklin FC
通讯作者：
Franklin FC
影响因子：
7.2
作者：
Hurel, Aurelie;Phillips, Dylan;Christophorou, Nicolas
通讯作者：
Christophorou, Nicolas