2013 dengue outbreaks in Singapore and Malaysia caused by different viral strains.

2013 dengue outbreaks in Singapore and Malaysia caused by different viral strains.
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DOI:
10.4269/ajtmh.14-0588
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发表时间:
2015-06
期刊:
The American journal of tropical medicine and hygiene
影响因子:
--
通讯作者:
Kheong CC
Kheong CC
中科院分区:
其他
文献类型:
--
作者:
Ng LC;Chem YK;Koo C;Mudin RNB;Amin FM;Lee KS;Kheong CC

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在一项名为UNITE Dengue的跨境监测项目中,对14,079种流行登革热病毒进行了表征,结果显示,2013年在新加坡和马来西亚爆发的疫情与主要血清型的替换有关。虽然新加坡的主要病毒从DENV 2转变为DENV 1,但DENV 2在邻国马来西亚成为主要病毒。DENV 2的优势在观察到较高死亡率的南部各州最为明显。
Characterization of 14,079 circulating dengue viruses in a cross-border surveillance program, UNITEDengue, revealed that the 2013 outbreaks in Singapore and Malaysia were associated with replacement of predominant serotype. While the predominant virus in Singapore switched from DENV2 to DENV1, DENV2 became predominant in neighboring Malaysia. Dominance of DENV2 was most evident on the southern states where higher fatality rates were observed.
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