Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins.
Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins.
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DOI：
10.3390/toxins10040156
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发表时间：
2018-04-13
期刊：
影响因子：
4.2
通讯作者：
Ibelings BW
中科院分区：
文献类型：
--
作者：
Mantzouki E;Lürling M;Fastner J;de Senerpont Domis L;Wilk-Woźniak E;Koreivienė J;Seelen L;Teurlincx S;Verstijnen Y;Krztoń W;Walusiak E;Karosienė J;Kasperovičienė J;Savadova K;Vitonytė I;Cillero-Castro C;Budzyńska A;Goldyn R;Kozak A;Rosińska J;Szeląg-Wasielewska E;Domek P;Jakubowska-Krepska N;Kwasizur K;Messyasz B;Pełechaty A;Pełechaty M;Kokocinski M;García-Murcia A;Real M;Romans E;Noguero-Ribes J;Duque DP;Fernández-Morán E;Karakaya N;Häggqvist K;Demir N;Beklioğlu M;Filiz N;Levi EE;Iskin U;Bezirci G;Tavşanoğlu ÜN;Özhan K;Gkelis S;Panou M;Fakioglu Ö;Avagianos C;Kaloudis T;Çelik K;Yilmaz M;Marcé R;Catalán N;Bravo AG;Buck M;Colom-Montero W;Mustonen K;Pierson D;Yang Y;Raposeiro PM;Gonçalves V;Antoniou MG;Tsiarta N;McCarthy V;Perello VC;Feldmann T;Laas A;Panksep K;Tuvikene L;Gagala I;Mankiewicz-Boczek J;Yağcı MA;Çınar Ş;Çapkın K;Yağcı A;Cesur M;Bilgin F;Bulut C;Uysal R;Obertegger U;Boscaini A;Flaim G;Salmaso N;Cerasino L;Richardson J;Visser PM;Verspagen JMH;Karan T;Soylu EN;Maraşlıoğlu F;Napiórkowska-Krzebietke A;Ochocka A;Pasztaleniec A;Antão-Geraldes AM;Vasconcelos V;Morais J;Vale M;Köker L;Akçaalan R;Albay M;Špoljarić Maronić D;Stević F;Žuna Pfeiffer T;Fonvielle J;Straile D;Rothhaupt KO;Hansson LA;Urrutia-Cordero P;Bláha L;Geriš R;Fránková M;Koçer MAT;Alp MT;Remec-Rekar S;Elersek T;Triantis T;Zervou SK;Hiskia A;Haande S;Skjelbred B;Madrecka B;Nemova H;Drastichova I;Chomova L;Edwards C;Sevindik TO;Tunca H;Önem B;Aleksovski B;Krstić S;Vucelić IB;Nawrocka L;Salmi P;Machado-Vieira D;de Oliveira AG;Delgado-Martín J;García D;Cereijo JL;Gomà J;Trapote MC;Vegas-Vilarrúbia T;Obrador B;Grabowska M;Karpowicz M;Chmura D;Úbeda B;Gálvez JÁ;Özen A;Christoffersen KS;Warming TP;Kobos J;Mazur-Marzec H;Pérez-Martínez C;Ramos-Rodríguez E;Arvola L;Alcaraz-Párraga P;Toporowska M;Pawlik-Skowronska B;Niedźwiecki M;Pęczuła W;Leira M;Hernández A;Moreno-Ostos E;Blanco JM;Rodríguez V;Montes-Pérez JJ;Palomino RL;Rodríguez-Pérez E;Carballeira R;Camacho A;Picazo A;Rochera C;Santamans AC;Ferriol C;Romo S;Soria JM;Dunalska J;Sieńska J;Szymański D;Kruk M;Kostrzewska-Szlakowska I;Jasser I;Žutinić P;Gligora Udovič M;Plenković-Moraj A;Frąk M;Bańkowska-Sobczak A;Wasilewicz M;Özkan K;Maliaka V;Kangro K;Grossart HP;Paerl HW;Carey CC;Ibelings BW
深入了解环境变化如何决定蓝藻毒素的生产和分布是必要的风险评估。目前的管理准则侧重于肝毒素（微囊藻毒素）。越来越多的注意力被给予其他类别，如神经毒素（例如，类毒素-A）和细胞毒素（例如，cylindrospermopsin）由于其效力。大多数研究考察了单个毒素变体与环境因素（如营养素、温度和光照）之间的关系。2015年夏天，我们在欧洲各地收集了样本，以研究营养和温度梯度对大陆尺度毒素产生变化的影响。温度的直接和间接影响是蓝藻毒素空间分布、毒素浓度和毒素量的主要驱动因素。广义线性模型表明，毒素多样性指数（TDI）增加与纬度，而它与水的稳定性下降。TDI的增加是通过毒素变体（如MC-YR、类毒素和柱孢菌蛋白酶）的显著增加来解释的，伴随着MC-LR的减少。随着全球变暖的持续，湖泊温度升高的直接和间接影响将推动欧洲蓝藻毒素分布的变化，可能会促进一些高毒性物种或菌株的选择。
Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.
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DOI：
10.1016/j.bjp.2014.07.019
发表时间：
2014-08-01
期刊：
Revista Brasileira de Farmacognosia
影响因子：
--
作者：
Bortoli, Stella;Oliveira-Silva, Diogo;Pinto, Ernani
通讯作者：
Pinto, Ernani
影响因子：
6.6
作者：
Freitas, Emanuela Cristina;Pinheiro, Carlos;Loureiro, Susana
通讯作者：
Loureiro, Susana
影响因子：
0.9
作者：
Cerasino, Leonardo;Salmaso, Nico
通讯作者：
Salmaso, Nico
影响因子：
5.4
作者：
Faassen EJ;Lürling M
通讯作者：
Lürling M
影响因子：
5.4
作者：
Holland A;Kinnear S
通讯作者：
Kinnear S