Hypoxia-induced short-term potentiation of respiratory-modulated facial motor output in the rat.
Hypoxia-induced short-term potentiation of respiratory-modulated facial motor output in the rat.
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DOI：
10.1016/j.resp.2010.06.015
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发表时间：
2010-08-31
影响因子：
2.3
通讯作者：
Fuller, David D.
中科院分区：
文献类型：
--
作者：
Lee, Kun-Ze;Fuller, David D.
呼吸调制的面神经放电包括吸气前（Pre-I）和吸气（I）成分。Tonic VII爆发也存在于整个呼吸周期中。我们测试的假设，缺氧诱导的可塑性VII运动活动的差异表达在前I，I和紧张性爆发。膈神经和VII神经图记录在麻醉，迷走神经切断和通气的成年大鼠。采用3分钟等二氧化碳低氧刺激（PaO 2 = 33 ± 2 mmHg）诱发呼吸短时程增强（STP）。前I，I和强直性VII活性立即增加，在缺氧的初始阶段（即急性反应），然后逐渐增加，缺氧维持。缺氧后，IVII活性保持升高（即缺氧后STP），但前I和强直活性立即恢复到基线值。我们的结论是，STP缺氧后优先表达在I相比，前I和紧张VII活动。
Respiratory-modulated facial (VII) nerve discharge includes pre-inspiratory (Pre-I) and inspiratory (I) components. Tonic VII bursting is also present across the respiratory cycle. We tested the hypothesis that hypoxia-induced plasticity of VII motor activity is differentially expressed in Pre-I, I and tonic bursting. Phrenic and VII neurograms were recorded in urethane-anesthetized, vagotomized and ventilated adult rats. A 3 minute isocapnic hypoxic challenge (PaO2 = 33 ± 2 mmHg) was used to evoke respiratory short-term potentiation (STP). Pre-I, I and tonic VII activity increased immediately at the initial stage of hypoxia (i.e. acute response) and then progressively increased as hypoxia was maintained. Following hypoxia, I VII activity remained elevated (i.e. post-hypoxia STP) but both Pre-I and tonic activity immediately returned to baseline values. We conclude that STP following hypoxia is preferentially expressed in I compared to Pre-I and tonic VII activity.
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影响因子：
2.3
作者：
Iizuka, Makito;Fregosi, Ralph F.
通讯作者：
Fregosi, Ralph F.
影响因子：
3.3
作者：
Lee, Kun-Ze;Fuller, David D.
通讯作者：
Fuller, David D.
影响因子：
2.5
作者：
Bailey, E. Fiona;Fridel, Keith W.;Rice, Amber D.
通讯作者：
Rice, Amber D.
影响因子：
3.3
作者：
FULLER, D;SULLIVAN, J;FREGOSI, RF
通讯作者：
FREGOSI, RF
DOI：
10.1016/0034-5687(88)90065-5
发表时间：
1988-08-01
期刊：
RESPIRATION PHYSIOLOGY
影响因子：
--
作者：
HWANG, JC;CHIEN, CT;STJOHN, WM
通讯作者：
STJOHN, WM