PICU Survivorship: Factors Affecting Feasibility and Cohort Retention in a Long-Term Outcomes Study.
PICU Survivorship: Factors Affecting Feasibility and Cohort Retention in a Long-Term Outcomes Study.
复制标题
DOI：
10.3390/children9071041
复制
发表时间：
2022-07-13
期刊：
影响因子：
2.4
通讯作者：
Pinto, Neethi P.
中科院分区：
文献类型：
--
作者：
Sobotka, Sarah A.;Lynch, Emma J.;Dholakia, Ayesha, V;Mayampurath, Anoop;Pinto, Neethi P.
我们对儿科重症监护病房 (PICU) 幸存者纵向结果的理解受到随访间隔、人群和评估结果的异质性的限制。我们试图证明（1）纵向多维结果评估的可行性和（2）促进队列保留的方法。本研究的目的是提供 PICU 幸存者队列的随访方法的详细信息，而不是提供该队列的长期随访结果。我们招募了 152 名入住 PICU 的 0 至 17 岁儿童进行前瞻性纵向队列研究。我们使用 PICU 结果组合 (POP) 调查检查了资源利用率、危重疾病的家庭影响和神经发育，其中包括针对具体研究的调查和经过验证的工具：1. 功能状态量表，2. 儿科残疾评估量表计算机自适应测试，3. 儿科生活质量量表，4. 优势和困难问卷，以及 5. 范德比尔特注意力缺陷多动评估量表混乱。 POP 调查在 1、3 和 6 个月时的完成率分别为 89%、78% 和 84%。 1 年、2 年和 3 年的随访率分别为 80%、55% 和 43%。在城市、三级护理、学术医院内，为 PICU 幸存者实施纵向多维结果组合是可行的。一年后的人员流失表明了该人群面临的长期后续挑战。我们的研究结果为儿科危重病后实施核心成果集的持续努力提供了信息。
Our understanding of longitudinal outcomes of Pediatric Intensive Care Unit (PICU) survivors is limited by the heterogeneity of follow-up intervals, populations, and outcomes assessed. We sought to demonstrate (1) the feasibility of longitudinal multidimensional outcome assessment and (2) methods to promote cohort retention. The objective of this presented study was to provide details of follow-up methodology in a PICU survivor cohort and not to present the outcomes at long-term follow-up for this cohort. We enrolled 152 children aged 0 to 17 years admitted to the PICU in a prospective longitudinal cohort study. We examined resource utilization, family impact of critical illness, and neurodevelopment using the PICU Outcomes Portfolio (POP) Survey which included a study-specific survey and validated tools: 1. Functional Status Scale, 2. Pediatric Evaluation of Disability Inventory Computer Adaptive Test, 3. Pediatric Quality of Life Inventory, 4. Strengths and Difficulties Questionnaire, and 5. Vanderbilt Assessment Scales for Attention Deficit-Hyperactivity Disorder. POP Survey completion rates were 89%, 78%, and 84% at 1, 3, and 6 months. Follow-up rates at 1, 2, and 3 years were 80%, 55%, and 43%. Implementing a longitudinal multidimensional outcome portfolio for PICU survivors is feasible within an urban, tertiary-care, academic hospital. Our attrition after one year demonstrates the long-term follow-up challenges in this population. Our findings inform ongoing efforts to implement core outcome sets after pediatric critical illness.
登录
查看更多内容
影响因子：
8.8
作者：
Fink EL;Maddux AB;Pinto N;Sorenson S;Notterman D;Dean JM;Carcillo JA;Berg RA;Zuppa A;Pollack MM;Meert KL;Hall MW;Sapru A;McQuillen PS;Mourani PM;Wessel D;Amey D;Argent A;Brunow de Carvalho W;Butt W;Choong K;Curley MAQ;Del Pilar Arias Lopez M;Demirkol D;Grosskreuz R;Houtrow AJ;Knoester H;Lee JH;Long D;Manning JC;Morrow B;Sankar J;Slomine BS;Smith M;Olson LM;Watson RS;Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN)
通讯作者：
Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN)
影响因子：
8.8
作者：
Fiser, DH;Tilford, JM;Roberson, PK
通讯作者：
Roberson, PK
影响因子：
4.1
作者：
Farris, Reid W. D.;Weiss, Noel S.;Zimmerman, Jerry J.
通讯作者：
Zimmerman, Jerry J.
影响因子：
3.6
作者：
Anderson, Nathan P.;Feldman, Jamie A.;Lindhiem, Oliver
通讯作者：
Lindhiem, Oliver
影响因子：
4.1
作者：
Bone, Meredith F.;Feinglass, Joseph M.;Goodman, Denise M.
通讯作者：
Goodman, Denise M.