Voxel-based morphometry reveals brain gray matter volume changes in successful dieters.
Voxel-based morphometry reveals brain gray matter volume changes in successful dieters.
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DOI：
10.1002/oby.21551
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发表时间：
2016-09
期刊：
影响因子：
6.9
通讯作者：
Savage, Cary R.
中科院分区：
文献类型：
--
作者：
Honea, Robyn A.;Szabo-Reed, Amanda N.;Lepping, Rebecca J.;Perea, Rodrigo;Breslin, Florence;Martin, Laura E.;Brooks, William M.;Donnelly, Joseph E.;Savage, Cary R.
To compare regional brain volume predictors of percent weight loss (WL) in dieters with obesity (DwO) and in the same participants categorized as “successful” (>7% WL) or “unsuccessful” dieters (<7% WL). DwO (n=72) or healthy weight (HW) (n=22), and completed a structural MRI at baseline and 3-months. All DwO participants were enrolled in a 12-week program consisting of a reduced calorie diet, increased physical activity, and behavioral modification. We used SPM8-based voxel-based morphometry processing streams for measurements of regional gray (GMV) and white matter volume (WMV), and longitudinal changes in volume. We then tested for correlations between WL and baseline brain volume, change in brain volume, as well as differences between groups. We found that %WL was positively correlated with baseline GMV in right parahippocampal and orbitofrontal gyri in DwO. Successful dieters showed greater GMV loss in the left precentral gyrus and the insula compared with unsuccessful dieters. A negative correlation was found between %WL and GMV change from baseline in the left prefrontal regions. Findings illustrate that WL is related to volumetric changes in brain areas previously linked to interoception and food motivation.
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影响因子：
5.8
作者：
Haltia, Lauri T.;Viljanen, Antti;Kaasinen, Valtteri
通讯作者：
Kaasinen, Valtteri
DOI：
10.1073/pnas.1015950108
发表时间：
2011-02-15
影响因子：
11.1
作者：
Erickson, Kirk I.;Voss, Michelle W.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
影响因子：
4.2
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ADNI
影响因子：
3.2
作者：
Bomba M;Riva A;Morzenti S;Grimaldi M;Neri F;Nacinovich R
通讯作者：
Nacinovich R
影响因子：
7.7
作者：
Leibel, Rudolph L.;Seeley, Randy J.;Ratner, Robert
通讯作者：
Ratner, Robert