Portable eye-tracking as a reliable assessment of oculomotor, cognitive and reaction time function: Normative data for 18-45 year old.
Portable eye-tracking as a reliable assessment of oculomotor, cognitive and reaction time function: Normative data for 18-45 year old.
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DOI：
10.1371/journal.pone.0260351
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Kiderman A
中科院分区：
文献类型：
--
作者：
Kullmann A;Ashmore RC;Braverman A;Mazur C;Snapp H;Williams E;Szczupak M;Murphy S;Marshall K;Crawford J;Balaban CD;Hoffer M;Kiderman A
高精度眼动跟踪技术测量的眼动是一种灵敏、客观、无创的神经通路检测方法。视力测试（例如，扫视和平滑追踪），涉及认知处理的测试（例如，反扫视和预测性扫视），反应时间测试越来越多地显示出在研究环境中诊断和监测轻度创伤性脑损伤（mTBI）的实用性。目前，由于缺乏规范性数据集，这些测试在临床实践中的应用受到阻碍。本研究的目的是建立一个规范的数据库，作为比较患者结果的参考。对年龄在18-45岁之间的男性和女性志愿者进行了视力、认知和反应时间测试，这些志愿者没有任何神经系统、前庭障碍或其他头部损伤。测试是使用配备视频眼动仪（VOG）的旋转椅或便携式虚拟现实般的VOG护目镜设备与红外线眼动跟踪技术。统计分析显示，当参与者数据被分为儿科（即，18-21岁，符合FDA标准）和成人（即，21-45岁）。性别（自我报告）对听觉反应时间有影响，男性比女性快。使用合并数据构建规范性数据库，使用95%参考区间（RI）和RI上限和下限的90%置信区间。这些RI的可用性容易允许临床医生识别有缺陷的特定指标，因此有助于快速分类，通知和监测治疗和/或康复方案，并有助于返回职责/活动决策。该数据库经FDA批准可用于临床实践（K192186）。
Eye movements measured by high precision eye-tracking technology represent a sensitive, objective, and non-invasive method to probe functional neural pathways. Oculomotor tests (e.g., saccades and smooth pursuit), tests that involve cognitive processing (e.g., antisaccade and predictive saccade), and reaction time tests have increasingly been showing utility in the diagnosis and monitoring of mild traumatic brain injury (mTBI) in research settings. Currently, the adoption of these tests into clinical practice is hampered by a lack of a normative data set. The goal of this study was to construct a normative database to be used as a reference for comparing patients’ results. Oculomotor, cognitive, and reaction time tests were administered to male and female volunteers, aged 18–45, who were free of any neurological, vestibular disorders, or other head injuries. Tests were delivered using either a rotatory chair equipped with video-oculography goggles (VOG) or a portable virtual reality-like VOG goggle device with incorporated infrared eye-tracking technology. Statistical analysis revealed no effects of age on test metrics when participant data were divided into pediatric (i.e.,18–21 years, following FDA criteria) and adult (i.e., 21–45 years) groups. Gender (self-reported) had an effect on auditory reaction time, with males being faster than females. Pooled data were used to construct a normative database using 95% reference intervals (RI) with 90% confidence intervals on the upper and lower limits of the RI. The availability of these RIs readily allows clinicians to identify specific metrics that are deficient, therefore aiding in rapid triage, informing and monitoring treatment and/or rehabilitation protocols, and aiding in the return to duty/activity decision. This database is FDA cleared for use in clinical practice (K192186).
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影响因子：
9.9
作者：
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通讯作者：
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影响因子：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1093/geronb/57.2.p101
发表时间：
2002-03-01
影响因子：
6.2
作者：
Hultsch, DF;MacDonald, SWS;Dixon, RA
通讯作者：
Dixon, RA