Diagnostic accuracy of microEEG: a miniature, wireless EEG device.

Diagnostic accuracy of microEEG: a miniature, wireless EEG device.
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DOI:
10.1016/j.yebeh.2014.03.015
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发表时间:
2014-05
期刊:
Epilepsy & behavior : E&B
影响因子:
--
通讯作者:
Zehtabchi S
Zehtabchi S
中科院分区:
其他
文献类型:
--
作者:
Grant AC;Abdel-Baki SG;Omurtag A;Sinert R;Chari G;Malhotra S;Weedon J;Fenton AA;Zehtabchi S

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测量脑电设备的诊断准确率(DA)是非常规的,而且由于评价器可靠性的不完善而变得复杂。我们试图在精神状态改变的急诊科(ED)患者中比较微型、无线、电池供电的EEG设备(“microEEG”)和参考脑电图机的DA。225例ED合并AMS患者行3次脑电地形图检查。使用信号分离器,用EEG杯电极同时记录EEG1(Nicolet Monitor,参考)和EEG2(微EEG)。在EEG1/EEG2之前或之后,使用电极帽用微型EEG记录EEG3。官方的EEG1解释被认为是黄金标准(EEG1-GS)。EEG1、EEG2和EEG3被两个独立的读者去识别和盲目解读。使用广义混合线性模型估计这些解释相对于EEG1-GS的敏感性和特异性,并计算诊断优势比(DOR)。79%的EEG1-GS异常。代表评价者间信度的DOR和κf在EEG1、EEG2和EEG3之间都没有显著差异。EEG1/EEG2的平均设置时间为27分钟,EEG3的平均设置时间为12分钟。EEG3记录的平均电极阻抗为12.6kΩ(SD31.9kΩ)。显微脑电的DA与参比系统相当,当脑电电极阻抗较高且不平衡时,DA不会降低。EEG设备DA的测量是许多科学仪器的常见做法,它提供了对设备性能的独立和定量评估。
Measuring the diagnostic accuracy (DA) of an EEG device is unconventional and complicated by imperfect interrater reliability. We sought to compare the DA of a miniature, wireless, battery-powered EEG device (“microEEG”) to a reference EEG machine in emergency department (ED) patients with altered mental status (AMS). 225 ED patients with AMS underwent 3 EEGs. EEG1 (Nicolet Monitor, “reference”) and EEG2 (microEEG) were recorded simultaneously with EEG cup electrodes using a signal splitter. EEG3 was recorded with microEEG using an electrode cap, immediately before or after EEG1/EEG2. The official EEG1 interpretation was considered the gold standard (EEG1-GS). EEG1, 2 and 3 were de-identified and blindly interpreted by two independent readers. A generalized mixed linear model was used to estimate the sensitivity & specificity of these interpretations relative to EEG1-GS, and to compute a diagnostic odds ratio (DOR). 79% of EEG1-GS were abnormal. Neither the DOR nor κf representing interrater reliabilities differed significantly between EEG1, EEG2, and EEG3. Mean setup time was 27 minutes for EEG1/EEG2 and 12 minutes for EEG3. Mean electrode impedance of EEG3 recordings was 12.6 kΩ (SD 31.9 kΩ). DA of microEEG was comparable to that of the reference system and was not reduced when the EEG electrodes had high and unbalanced impedances. A common practice with many scientific instruments, measurement of EEG device DA provides an independent and quantitative assessment of device performance.
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发表时间: 2006-05-01
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