Barriers to medication adherence in behaviorally and perinatally infected youth living with HIV.
Barriers to medication adherence in behaviorally and perinatally infected youth living with HIV.
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DOI：
10.1007/s10461-012-0364-1
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发表时间：
2013-01
影响因子：
4.4
通讯作者：
Belzer, Marvin
中科院分区：
文献类型：
--
作者：
MacDonell, Karen;Naar-King, Sylvie;Huszti, Heather;Belzer, Marvin
关键词：
这项研究探讨了在围产期和行为上感染艾滋病毒的青少年和年轻人的抗逆转录病毒药物依从性的障碍，在一个横断面，多地点的样本。该研究包括一个方便的样本的一个子集，从横截面分析。参与者为12-24岁的HIV感染青年，他们在过去7天内接受了HIV药物处方并报告了药物缺失（n = 484，占方案样本的28.4%）。围产期感染和行为感染的青年的最高障碍相似，但围产期感染的青年报告的障碍明显更多。遗忘、不想服药和不想被提醒感染艾滋病毒是报告的最常见障碍。围产期感染青年的屏障数量与漏服剂量百分比、病毒载量和心理困扰显著相关，行为感染青年的屏障数量与漏服剂量、心理困扰和物质使用显著相关。改善艾滋病毒药物依从性的干预措施不仅应解决健忘和选择不服药的问题，还应考虑感染途径。
The study explored barriers to antiretroviral medication adherence in perinatally and behaviorally HIV infected adolescents and young adults in a cross-sectional, multisite sample. The study included a subset of a convenience sample from a cross-sectional analysis. Participants were youth with HIV ages 12–24 who were prescribed HIV medication and reported missing medication in the past 7 days (n = 484, 28.4 % of protocol sample). The top barriers were similar for perinatally and behaviorally infected youth, but perinatally infected youth reported significantly more barriers. Forgetting, not feeling like taking medication and not wanting to be reminded of HIV infection were the most common barriers reported. Number of barriers was significantly correlated with percent of doses missed, viral load, and psychological distress for perinatally infected youth and with doses missed, psychological distress, and substance use for behaviorally infected youth. Interventions to improve adherence to HIV medications should not only address forgetfulness and choosing not to take medications, but also consider route of infection.
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影响因子：
2.1
作者：
Koenig, Linda J.;Nesheim, Steven;Abramowitz, Susan
通讯作者：
Abramowitz, Susan
影响因子：
3.8
作者：
Bangsberg, DR;Perry, S;Moss, A
通讯作者：
Moss, A
DOI：
10.1097/00042560-200112150-00006
发表时间：
2001-12-15
期刊：
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
影响因子：
--
作者：
Ammassari, A;Murri, R;Antinori, A
通讯作者：
Antinori, A
影响因子：
4.9
作者：
MacDonell, Karen E.;Naar-King, Sylvie;Huszti, Heather
通讯作者：
Huszti, Heather
影响因子：
2.6
作者：
Woods, Steven Paul;Moran, Lisa M.;Atkinson, J. Hampton
通讯作者：
Atkinson, J. Hampton