Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.
Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.
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DOI：
10.1371/journal.pone.0190741
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Maeda Y
中科院分区：
文献类型：
--
作者：
Ikebe K;Gondo Y;Kamide K;Masui Y;Ishizaki T;Arai Y;Inagaki H;Nakagawa T;Kabayama M;Ryuno H;Okubo H;Takeshita H;Inomata C;Kurushima Y;Mihara Y;Hatta K;Fukutake M;Enoki K;Ogawa T;Matsuda KI;Sugimoto K;Oguro R;Takami Y;Itoh N;Takeya Y;Yamamoto K;Rakugi H;Murakami S;Kitamura M;Maeda Y
越来越多的证据表明，口腔健康可能是与老年人认知功能相关的一个重要因素。然而，以前关于这一主题的许多研究使用不敏感的口腔指标或不包括某些必要的协变量。因此，我们通过控制饮食摄入量、血管危险因素、炎症生物标记物、抑郁和遗传因素，在大样本老年人中检验了咬合力和认知功能之间的关系。在这项对居住在社区的日本老年人的横断面研究中，我们检查了从994名70岁的人和968名80岁的人收集的数据。认知功能采用日文版蒙特利尔认知评估(MoCA-J)进行测量。根据剩余牙数、牙周袋深度和最大咬合力评价口腔状态和功能。通过双变量和多变量分析探讨MoCA-J评分与咬合力之间的关系。在两个年龄组中，受教育程度、经济状况、抑郁评分、绿色和黄色蔬菜的摄入量、牙数和咬合力与MoCA-J评分显著相关。在80岁的老年人中，C反应蛋白和牙周状况与MoCA-J评分有微弱但显著的相关性。在通过双变量分析控制了所有重要变量后，最大咬合力和认知功能之间的相关性仍然存在。路径分析证实了认知功能与咬合力直接相关的假设，也证实了通过食物摄入间接与咬合力相关的假设。在控制了可能的因素后，最大咬合力与认知功能直接正相关，也通过饮食摄入量间接正相关。
Growing evidence suggests that oral health may be an important factor associated with cognitive function in aged populations. However, many previous studies on this topic used insensitive oral indicators or did not include certain essential covariates. Thus, we examined the association between occlusal force and cognitive function in a large sample of older adults, controlling for dietary intake, vascular risk factors, inflammatory biomarkers, depression, and genetic factors. In this cross-sectional study of older community-dwelling Japanese adults, we examined data collected from 994 persons aged 70 years and 968 persons aged 80 years. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Oral status and function were evaluated according to the number of remaining teeth, periodontal pocket depth, and maximal occlusal force. Associations between MoCA-J scores and occlusal force were investigated via bivariate and multivariate analyses. Education level, financial status, depression score, and intake of green and yellow vegetables, as well as number of teeth and occlusal force, were significantly correlated with MoCA-J scores in both age groups. Among individuals aged 80 years, CRP and periodontal status were weakly but significantly associated with MoCA-J score. After controlling for all significant variables via bivariate analyses, the correlation between maximal occlusal force and cognitive function persisted. A path analysis confirmed the hypothesis that cognitive function is associated with occlusal force directly as well as indirectly via food intake. After controlling for possible factors, maximal occlusal force was positively associated with cognitive function directly as well as indirectly through dietary intake.
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影响因子：
7.6
作者：
Hasegawa, Y.;Ono, T.;Nokubi, T.
通讯作者：
Nokubi, T.
DOI：
10.1111/j.1532-5415.2012.04154.x
发表时间：
2012-10-01
影响因子：
6.3
作者：
Lexomboon, Duangjai;Trulsson, Mats;Parker, Marti G.
通讯作者：
Parker, Marti G.
DOI：
10.1111/j.1532-5415.1999.tb03848.x
发表时间：
1999-07-01
影响因子：
6.3
作者：
Hoyl, MT;Alessi, CA;Rubenstein, LZ
通讯作者：
Rubenstein, LZ
影响因子：
--
作者：
Cerutti-Kopplin, D;Feine, J;Emami, E
通讯作者：
Emami, E
影响因子：
3.3
作者：
Fujiwara, Yoshinori;Suzuki, Hiroyuki;Shinkai, Shoji
通讯作者：
Shinkai, Shoji