Cognitive Flexibility and Impulsivity Deficits in Suicidal Adolescents.
Cognitive Flexibility and Impulsivity Deficits in Suicidal Adolescents.
复制标题
有自杀倾向的青少年的认知灵活性和冲动缺陷。
DOI：
10.1007/s10802-022-00952-y
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发表时间：
2022-12
影响因子：
2.5
通讯作者：
Dickstein, Daniel P.
中科院分区：
文献类型：
--
作者：
MacPherson, Heather A.;Kim, Kerri L.;Seymour, Karen E.;Wolff, Jennifer;Esposito-Smythers, Christianne;Spirito, Anthony;Dickstein, Daniel P.
关键词：
虽然在有自杀意念（SI）和自杀企图（SA）的青少年中已经记录了神经认知缺陷，但目前尚不清楚某些损伤是否能区分这些群体，这可能表明SA的风险增加。专注于冲动和认知控制的特定方面可能表明SA与SI青少年之间的区别。目前的研究探讨了冲动和认知控制的尺寸在141青少年SA（n=41）与SI没有SA（n=49）与典型的发展控制（TDC; n=51）。青少年通过剑桥神经心理测试自动化电池完成横截面神经认知任务，除了人口统计学和临床措施。分析包括ANOVA和ANCOVA。结果表明，SA青少年表现出较少的集转移/认知灵活性（适应/脱离刺激的能力降低）和更大的冲动决策（决策前收集/评估信息的能力降低）相比，TDC。此外，TDC和SA青少年比SI青少年具有更大的反应抑制（停止已经开始/变得优势的运动反应的能力增加）。当单独分析女性青少年时，也发现了类似的结果。男性青少年无显著差异，可能是由于子样本较小（n=40）。空间规划/问题解决或视觉空间工作记忆没有显着的结果。研究结果表明：1）SA青少年与TDC相比，集合转移/认知灵活性更少，冲动决策更大; 2）TDC和SA青少年与SI相比，反应抑制更大。这些信息可能有助于改善风险评估（增加神经认知任务）和针对性治疗（纳入认知补救）。
Although neurocognitive deficits have been documented in adolescents with suicidal ideation (SI) and suicide attempts (SA), it is unclear whether certain impairments differentiate these groups, potentially suggesting heightened risk for SA. Focus on specific facets of impulsivity and cognitive control may indicate distinctions between adolescents with SA vs. SI. The current study examined dimensions of impulsivity and cognitive control in 141 adolescents with SA (n=41) vs. SI without SA (n=49) vs. typically-developing controls (TDCs; n=51). Adolescents completed cross-sectional neurocognitive tasks via the Cambridge Neuropsychological Testing Automated Battery, in addition to demographic and clinical measures. Analyses involved ANOVAs and ANCOVAs. Results indicated that adolescents with SA demonstrated less set shifting/cognitive flexibility (reduced ability to adapt to/disengage from stimuli) and greater impulsive decision making (reduced ability to collect/evaluate information before making decisions) compared to TDCs. In addition, both TDCs and adolescents with SA had greater response inhibition (increased ability to stop motor responses that have begun/become prepotent) than those with SI. Similar results were found when analyzing female adolescents separately. There were no significant differences for male adolescents, potentially due to the small subsample (n=40). There were no significant findings for spatial planning/problem solving or visuospatial working memory. Findings suggest: 1) less set shifting/cognitive flexibility and greater impulsive decision making for adolescents with SA vs. TDCs; and 2) greater response inhibition for TDCs and adolescents with SA vs. SI. Such information may be useful for improving risk assessments (adding neurocognitive tasks) and targeted treatments (incorporating cognitive remediation) for this impaired population.
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DOI：
10.1016/j.jaac.2012.01.002
发表时间：
2012-04
影响因子：
13.3
作者：
Bridge JA;McBee-Strayer SM;Cannon EA;Sheftall AH;Reynolds B;Campo JV;Pajer KA;Barbe RP;Brent DA
通讯作者：
Brent DA
影响因子：
11.3
作者：
Dougherty, Donald M.;Mathias, Charles W.;Marsh-Richard, Dawn M.;Prevette, Kristen N.;Dawes, Michael A.;Hatzis, Erin S.;Palmes, Guy;Nouvion, Sylvain O.
通讯作者：
Nouvion, Sylvain O.
影响因子：
10.6
作者：
Dombrovski, Alexandre Y.;Szanto, Katalin;Siegle, Greg J.;Wallace, Meredith L.;Forman, Steven D.;Sahakian, Barbara;Reynolds, Charles F., III;Clark, Luke
通讯作者：
Clark, Luke
影响因子：
1.9
作者：
Ackerman, John P.;McBee-Strayer, Sandy M.;Bridge, Jeffrey A.
通讯作者：
Bridge, Jeffrey A.
影响因子：
5.9
作者：
Franklin, Joseph C.;Fox, Kathryn R.;Nock, Matthew K.
通讯作者：
Nock, Matthew K.