Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications.
Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications.
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DOI：
10.1002/adhm.201701161
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发表时间：
2018-04
影响因子：
10
通讯作者：
Engler AJ
中科院分区：
文献类型：
--
作者：
Placone JK;Engler AJ
在过去的十年中，增材制造或3D打印在组织工程中变得越来越普遍，因为已经开发了各种新的打印材料。在基于挤出的打印中，材料用于从无细胞打印到模拟天然组织的载有细胞的生物墨水的应用。除了单一组织应用之外，最近已经开发了基于多材料挤出的打印以制造模拟组织界面的支架。尽管有这些进步，但一些材料限制阻止了目前可用的基于挤出的3D打印机的广泛采用。本进度报告将概述这种常用的打印策略，并深入了解如何改进这种技术。因此，我们希望我们的前瞻性报告能够指导在打印之前纳入更严格的材料表征，从而促进跨平台利用和再现性。基于挤出的3D打印已经证明了制造无细胞和载有细胞的工程组织的重要前景本进展报告讨论了基于挤出的3D打印和该领域的最新进展，并举例说明了它们如何解决生物医学工程问题。这些亮点说明了引领3D打印材料开发、表征和设计的进步。
Additive manufacturing, or 3D printing, has become significantly more commonplace in tissue engineering over the past decade, as a variety of new printing materials have been developed. In extrusion-based printing, materials are used for applications that range from cell free printing to cell-laden bioinks that mimic natural tissues. Beyond single tissue applications, multi-material extrusion based printing has recently been developed to manufacture scaffolds that mimic tissue interfaces. Despite these advances, some material limitations prevent wider adoption of the extrusion-based 3D printers currently available. This progress report will provide an overview of this commonly used printing strategy, as well as provide insight into how this technique can be improved. As such, we hope that our prospective report guides the inclusion of more rigorous material characterization prior to printing, thereby facilitating cross-platform utilization and reproducibility. Extrusion-based 3D printing has demonstrated significant promise for the fabrication of cell-free and cell-laden engineered tissues This progress report discusses extrusion-based 3D printing and recent advances in this field with examples of how they are approaching biomedical engineering problems. These highlights illustrate the advancements that are leading the way for development, characterization, and design of materials for 3D printing.
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影响因子：
3.1
作者：
Gittard SD;Narayan RJ
通讯作者：
Narayan RJ
DOI：
10.1002/adma.201501099
发表时间：
2015-07-15
期刊：
Advanced materials (Deerfield Beach, Fla.)
影响因子：
--
作者：
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通讯作者：
Zhao X
影响因子：
3.1
作者：
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通讯作者：
Soman, Pranav
影响因子：
10
作者：
Gu, Qi;Tomaskovic-Crook, Eva;Crook, Jeremy M.
通讯作者：
Crook, Jeremy M.
影响因子：
0.9
作者：
Hatamleh, Muhanad M.;Bhamrah, Gurprit;Huppa, Chrisopher
通讯作者：
Huppa, Chrisopher