Laser direct writing of micro- and nano-scale medical devices.

Laser direct writing of micro- and nano-scale medical devices.
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DOI:
10.1586/erd.10.14
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发表时间:
2010-05
影响因子:
3.1
通讯作者:
Narayan RJ
Narayan RJ
中科院分区:
工程技术3区
文献类型:
--
作者:
Gittard SD;Narayan RJ

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近年来,基于激光的材料直接写入经历了显著的发展。以小的长度尺度和使用短的生产时间修改各种材料的能力为激光直写提供了用于制造医疗设备的独特能力。在许多基于激光的快速成型方法中,材料的微米级和亚微米级结构化由计算机生成的模型控制。各种基于激光的直写方法,包括选择性激光烧结/熔化,激光加工,矩阵辅助脉冲激光蒸发直写,立体光刻和双光子聚合,进行了描述。它们在微结构和纳米结构医疗设备的制造中的使用进行了讨论。激光直写可用于处理各种先进的医疗设备,包括患者专用假体、药物输送设备、生物传感器、支架和组织工程支架。
Laser-based direct writing of materials has undergone significant development in recent years. The ability to modify a variety of materials at small length scales and using short production times provides laser direct writing with unique capabilities for fabrication of medical devices. In many laser-based rapid prototyping methods, microscale and submicroscale structuring of materials is controlled by computer-generated models. Various laser-based direct write methods, including selective laser sintering/melting, laser machining, matrix-assisted pulsed-laser evaporation direct write, stereolithography and two-photon polymerization, are described. Their use in fabrication of microstructured and nanostructured medical devices is discussed. Laser direct writing may be used for processing a wide variety of advanced medical devices, including patient-specific prostheses, drug delivery devices, biosensors, stents and tissue-engineering scaffolds.
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