Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?
Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?
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DOI：
10.1155/2012/406357
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发表时间：
2012
影响因子：
--
通讯作者：
Castellano MM
中科院分区：
文献类型：
--
作者：
Muñoz A;Castellano MM
多年来，对植物在逆境条件下基因表达调控的研究主要集中在转录变化的分析上。然而，尽管在植物和其他真核生物中，翻译调控已被证明在对不同胁迫的反应中起着关键作用，但在这些生物中，关于翻译调控的知识却非常匮乏。非生物胁迫下蛋白质合成的调控被认为是一个保守的过程，因为一般来说，在真核生物中，翻译因子和翻译过程基本相似。然而，由于控制翻译机制的知识非常贫乏，这种保护在植物中并不那么清楚。事实上，翻译起始的一些基本调控因子，在其他系统中有很好的特征，在植物中仍有待确定。在本文中，我们将重点关注不同起始因子的调控以及细胞mrna用来绕过非生物胁迫下建立的翻译抑制的机制。为此，我们将回顾来自不同真核生物的知识，但特别关注最近在植物中发表的信息。
For years, the study of gene expression regulation of plants in response to stress conditions has been focused mainly on the analysis of transcriptional changes. However, the knowledge on translational regulation is very scarce in these organisms, despite in plants, as in the rest of the eukaryotes, translational regulation has been proven to play a pivotal role in the response to different stresses. Regulation of protein synthesis under abiotic stress was thought to be a conserved process, since, in general, both the translation factors and the translation process are basically similar in eukaryotes. However, this conservation is not so clear in plants as the knowledge of the mechanisms that control translation is very poor. Indeed, some of the basic regulators of translation initiation, well characterised in other systems, are still to be identified in plants. In this paper we will focus on both the regulation of different initiation factors and the mechanisms that cellular mRNAs use to bypass the translational repression established under abiotic stresses. For this purpose, we will review the knowledge from different eukaryotes but paying special attention to the information that has been recently published in plants.
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影响因子：
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作者：
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DOI：
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发表时间：
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影响因子：
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作者：
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