Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation.

Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation.
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DOI:
10.1016/j.pcad.2008.10.003
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发表时间:
2009-01
影响因子:
9.1
通讯作者:
Meier-Ewert, Hans K.
Meier-Ewert, Hans K.
中科院分区:
医学2区
文献类型:
--
作者:
Mullington, Janet M.;Haack, Monika;Toth, Maria;Serrador, Jorge A.;Meier-Ewert, Hans K.

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睡眠不足与注意力不集中和表现缺陷有关,这一点正得到广泛认可。很少有人知道,流行病学研究中的慢性睡眠问题也与总体死亡率和发病率的增加有关。本文总结了睡眠不足对心血管危险因素的已知影响,包括血压,葡萄糖代谢,激素调节和炎症,特别强调实验性睡眠丧失,使用完全和部分睡眠剥夺模型,在正常睡眠7-8小时的健康个体中,没有睡眠障碍。这些研究表明,睡眠不足会改变既定的心血管危险因素,使其朝着增加心脏病发病风险的方向发展。
That insufficient sleep is associated with poor attention and performance deficits is becoming widely recognized. Fewer people are aware that chronic sleep complaints in epidemiological studies have also been associated with an increase in overall mortality and morbidity. This article summarizes findings of known effects of insufficient sleep on cardiovascular risk factors including blood pressure, glucose metabolism, hormonal regulation and inflammation with particular emphasis on experimental sleep loss, using models of total and partial sleep deprivation, in healthy individuals who normally sleep in the range of 7-8 hours and have no sleep disorders. These studies show that insufficient sleep alters established cardiovascular risk factors in a direction that is known to increase the risk of cardiac morbidity.
DOI: 10.1016/0306-4530(94)90005-1
发表时间: 1994-01-01
影响因子: 3.7
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